Application of Lead-Free Metal Halide Perovskite Heterojunctions for the Carbohalogenation of C–C Multiple Bonds
A graphitic carbon nitride/lead-free double perovskite heterojunction (<i>g</i>-C<sub>3</sub>N<sub>4</sub>/Cs<sub>2</sub>AgBiCl<sub>6</sub>) has been adopted as a heterogeneous photocatalyst under visible light irradiation. The employed material enabled the atom transfer radical addition-type carbohalogenation of multiple C-C bonds, including (internal) alkenes and alkynes, with alkyl halides. The protocol showed a remarkable functional group tolerance, compatible with the late-stage functionalization of natural and pharmaceutical derivatives, and could be easily scaled up, delivering >1 g of the desired products.
Authors
- Mirko Prato (ORCID: https://orcid.org/0000-0002-2188-8059)
- Costanza Tedesco
- Davide Ravelli (ORCID: https://orcid.org/0000-0003-2201-4828)
- Lorenzo Malavasi (ORCID: https://orcid.org/0000-0003-4724-2376)
- Camilla Callegari (ORCID: https://orcid.org/0009-0003-8994-4728)
- Alessia Corbo
Institutions
- University of Pavia (IT)
- Italian Institute of Technology (IT)
- National Interuniversity Consortium of Materials Science and Technology (IT)
Publication Details
- Journal
- Organic Letters
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1021/acs.orglett.5c00780
- Citations
- 3
- Primary Topic
- Catalytic Cross-Coupling Reactions
- Type
- article
- Field-Weighted Citation Impact
- 2.81
Funders
- Ministero dell'Università e della Ricerca
- HORIZON EUROPE European Innovation Council