Advancing fatigue life prediction of cortical bone under mode I loading using the DCB test

• Mode I fatigue tests were performed on pre-cracked cortical bone using DCB tests. • The CBBM combined with a noise reduction method was used as data reduction scheme. • A cohesive zone model was applied to predict fatigue damage propagation in bone. • Validation was performed comparing the numerical vs experimental C = f(N) curves. A comprehensive understanding of the mechanisms underlying bone fatigue failure is crucial for advancing treatment strategies. In this regard, this study presents a novel approach to quantify crack propagation in cortical bone tissue through fatigue testing under mode I loading. To closely replicate real bone damage mechanisms, pre-cracked bone samples were subjected to cyclic loading. A compliance-based beam method and cubic B -spline interpolation method were employed to accurately extract fatigue coefficients and reduce experimental noise, yielding refined modified Paris law coefficients. A cohesive zone model for high-cycle fatigue was used to simulate crack propagation, capturing the nonlinear material response by means of the cohesive zone length, mimicking the non-negligible fracture process zone. The goal is to validate the followed experimental procedure. This study offers valuable insights into the fatigue and fracture mechanisms in cortical bone, providing a more accurate and realistic framework for characterizing fatigue life compared to previous methodologies. Coefficients produced from the cohesive model may be readily integrated into simulation tools commonly used in many areas of engineering, allowing biomechanical experts to create more robust designs that simulate actual world conditions for application in implants and orthopaedic structures.