Dapansutrile mitigates concanavalin A- induced autoimmune hepatitis: Involvement of NLRP3/IL-1β and JNK/ p38 MAPK pathways

Our results showed that intraperitoneal administration of Dapan could be a therapeutic opportunity to inhibit the development of AIH via inhibition of inflammatory pathways.

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Publication Details

Journal
Biomedicine & Pharmacotherapy
Published
2025-04-01
DOI
https://doi.org/10.1016/j.biopha.2025.118026
Citations
5
Primary Topic
Liver Diseases and Immunity
Type
article
Field-Weighted Citation Impact
6.61

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article

Dapansutrile mitigates concanavalin A- induced autoimmune hepatitis: Involvement of NLRP3/IL-1β and JNK/ p38 MAPK pathways

Dalia H. El‐Kashef, Fahad Alenezi, Marwa E. Abdelmageed, Manar A. Nader
5 citations
Biomedicine & Pharmacotherapy
Liver Diseases and Immunity
6.61
article

Dapansutrile mitigates concanavalin A- induced autoimmune hepatitis: Involvement of NLRP3/IL-1β and JNK/ p38 MAPK pathways

Dalia H. El‐Kashef, Fahad Alenezi, Marwa E. Abdelmageed, Manar A. Nader
article en
5 citations

Abstract

Our results showed that intraperitoneal administration of Dapan could be a therapeutic opportunity to inhibit the development of AIH via inhibition of inflammatory pathways.

Biomedicine & PharmacotherapyVol. 186
Mansoura University (EG)
Mansoura University
Good health and well-being
Openalex Percentile: Top 3%
Liver Diseases and Immunity
6.61
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