A high-entropy coordination cage featuring an Au-porphyrin metalloligand for the photodynamic therapy of liver cancer
We report a Pd-based hexagonal prismatic coordination cage of Pd-TMPP(Au) featuring a highly entropic ligand combination, <i>viz.</i> H<sub>2</sub>TMPP, TMPP(Pd), and TMPP(Au) metalloligands to yield double-arrow-shaped polycrystals. Pd-TMPP(Au) exhibits concentration-dependent cytotoxicity against hepatocellular carcinoma cell lines HuH-7, Hep-G2, and PLC/PRF/5, which is augmented by light irradiation.
Authors
- Fenglin Cao
- David J. Young (ORCID: https://orcid.org/0000-0001-9947-6655)
- Zesheng Zhang (ORCID: https://orcid.org/0000-0002-0173-9355)
- Yiming Mao (ORCID: https://orcid.org/0000-0001-5437-775X)
- Wen‐Hua Zhang (ORCID: https://orcid.org/0000-0001-9047-8881)
- Ning Ye (ORCID: https://orcid.org/0000-0001-8222-5761)
- Meng-Lin Dong
Institutions
- Shanghai Jiao Tong University (CN)
- Soochow University (CN)
- Suzhou Kowloon Hospital (CN)
- University of Glasgow (GB)
Publication Details
- Journal
- Chemical Communications
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5cc00750j
- Primary Topic
- Metal complexes synthesis and properties
- Type
- article
- Field-Weighted Citation Impact
- 0.00