Long noncoding RNA semaphorin 6A-antisense RNA 1 reduces hepatocellular carcinoma by promoting semaphorin 6A mRNA degradation
Our findings suggest that SEMA6A-AS1 can inhibit HCC progression through decreasing SEMA6A expression by promoting its mRNA degradation. SEMA6A-AS1 may be a prognostic biomarker and therapeutic target for HCC.
Authors
- Siya Pei (ORCID: https://orcid.org/0009-0007-9628-7024)
- Songman Yu
- Xingwang Hu (ORCID: https://orcid.org/0000-0002-2320-3279)
- Li Juan Wu (ORCID: https://orcid.org/0000-0002-5468-2487)
- S J Li
- Min Zhang (ORCID: https://orcid.org/0000-0002-4863-9431)
- Yang Duan (ORCID: https://orcid.org/0000-0002-1522-0255)
Institutions
- Central South University (CN)
- National Clinical Research (US)
- Xiangya Hospital Central South University (CN)
Publication Details
- Journal
- World Journal of Gastroenterology
- Published
- 2025-04-02
- DOI
- https://doi.org/10.3748/wjg.v31.i13.102527
- Citations
- 2
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 1.87