[Translated article] Facial Discoid Dermatosis. A 13-Case Series

Facial discoid dermatosis (FDD) is a condition characterized by papules-plaques primarily affecting the face. FDD has been associated with psoriasis, seborrheic dermatitis, and pityriasis rubra pilaris. We conducted a retrospective multicenter study with 13 patients diagnosed with FDD in Spain (2014-2022). Patient demographics, clinical presentations, histopathological findings, and treatment outcomes were collected. FDD shows as erythematous-orange, nummular papules and/or plaques with dry scales that primarily affect the facial region. Histopathological analysis revealed a consistent pattern of psoriasiform hyperplasia with confluent parakeratosis, without neutrophils within the epidermal layers. This study provides essential insights into the clinical and histopathological features of FDD within a predominantly Caucasian patient cohort. The presence of distinct clinical features and consistent histological findings underscores the uniqueness of FDD. However, the variability in histological features and persistence of lesions despite various treatments highlight the need for further research to better understand the pathogenesis of FDD and develop effective therapies.

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Publication Details

Journal
Actas Dermo-Sifiliográficas
Published
2025-04-02
DOI
https://doi.org/10.1016/j.ad.2025.03.025
Primary Topic
Autoimmune Bullous Skin Diseases
Type
article
Field-Weighted Citation Impact
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article

[Translated article] Facial Discoid Dermatosis. A 13-Case Series

B Butrón-Bris, Alejandra Reolid, José M. Mascaró, Pedro Rodríguez‐Jiménez et al.
Actas Dermo-Sifiliográficas
Autoimmune Bullous Skin Diseases
article

[Translated article] Facial Discoid Dermatosis. A 13-Case Series

B Butrón-Bris, Alejandra Reolid, José M. Mascaró, Pedro Rodríguez‐Jiménez, Mar Llamas‐Velasco, C. Eguren, Sonsoles Berenguer‐Ruiz, J. Fraga, Luisa Martos‐Cabrera, Rosario Serrano‐Pardo, Pilar Iranzo, C. Buján
article en

Abstract

Facial discoid dermatosis (FDD) is a condition characterized by papules-plaques primarily affecting the face. FDD has been associated with psoriasis, seborrheic dermatitis, and pityriasis rubra pilaris. We conducted a retrospective multicenter study with 13 patients diagnosed with FDD in Spain (2014-2022). Patient demographics, clinical presentations, histopathological findings, and treatment outcomes were collected. FDD shows as erythematous-orange, nummular papules and/or plaques with dry scales that primarily affect the facial region. Histopathological analysis revealed a consistent pattern of psoriasiform hyperplasia with confluent parakeratosis, without neutrophils within the epidermal layers. This study provides essential insights into the clinical and histopathological features of FDD within a predominantly Caucasian patient cohort. The presence of distinct clinical features and consistent histological findings underscores the uniqueness of FDD. However, the variability in histological features and persistence of lesions despite various treatments highlight the need for further research to better understand the pathogenesis of FDD and develop effective therapies.

Actas Dermo-SifiliográficasVol. 116(6)
Clínica Rementería (ES), Complejo Hospitalario Universitario de Santiago (ES), Hospital Clínic de Barcelona (ES), Hospital Universitario de La Princesa (ES)
Openalex Percentile: Top 91%
Autoimmune Bullous Skin Diseases
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[Translated article] Facial Discoid Dermatosis. A 13-Case Series — B Butrón-Bris, Alejandra Reolid, et al. · Actas Dermo-Sifiliográficas (2025) | TGRS Research Map | TGRS