Geographic, socioeconomic and demographic inequalities in the incidence of metastatic prostate cancer at time of diagnosis in England: a population-based evaluation
There is significant geographic variation in metastatic prostate cancer incidence at diagnosis, with a higher incidence of metastatic cancer observed in areas with a lower overall prostate cancer incidence and in more socioeconomically deprived neighbourhoods, which likely contributes to poorer long-term outcomes. The findings highlight the need for a targeted, risk-based diagnostic approach as well as improved diagnostic facilities and referral pathways. Further research is needed to understand the factors driving this variation in order to reduce metastatic presentations and tackle inequalities in prostate cancer outcomes.
Authors
- Thomas E. Cowling (ORCID: https://orcid.org/0000-0003-1524-4393)
- Adrian David Cook (ORCID: https://orcid.org/0000-0003-4417-2632)
- Jan van der Meulen (ORCID: https://orcid.org/0000-0002-9451-2335)
- Marina Parry (ORCID: https://orcid.org/0000-0003-3278-9491)
- Ajay Aggarwal (ORCID: https://orcid.org/0000-0001-9645-6659)
- Joanna Dodkins
- Noel W. Clarke (ORCID: https://orcid.org/0000-0001-7776-8059)
- Julie Nossiter (ORCID: https://orcid.org/0000-0002-8597-7624)
- Emily Mayne
- Heather Payne (ORCID: https://orcid.org/0000-0001-8117-7411)
- Alison Tree
Institutions
- Royal Marsden NHS Foundation Trust (GB)
- Institute of Cancer Research (GB)
- Royal College of Surgeons of England (GB)
- Guy's and St Thomas' NHS Foundation Trust (GB)
- London School of Hygiene & Tropical Medicine (GB)
- The Christie NHS Foundation Trust (GB)
- The Prostate Centre (GB)
Publication Details
- Journal
- BMJ Oncology
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1136/bmjonc-2024-000643
- Citations
- 6
- Primary Topic
- Prostate Cancer Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 9.11