Sistemik immün-inflamasyon indeksi ve sistemik inflamatuar yanıt indeksi mikrodiseksiyon-testiküler sperm ekstraksiyonunda sperm varlığının belirleyicisi midir?

OBJECTIVE: To evaluate the usability of hematological inflammatory parameters in predicting sperm retrieval success during microdissection testicular sperm extraction (micro-TESE). MATERIAL and METHODS: Eighty patients diagnosed with non-obstructive azoospermia were included in the study. Age, follicle-stimulating hormone, total testosterone levels, and neutrophil, lymphocyte, monocyte, and platelet counts of the patients were recorded. Neutrophil-lymphocyte ratio, platelet-lymphocyte ratio, monocyte-lymphocyte ratio, systemic immune-inflammation index, and systemic inflammatory response index were calculated. The groups in which spermatozoa were obtained and those in which spermatozoa were not obtained during micro-TESE were compared. RESULTS: Although significantly older age (p<0.001) was detected in the group from which spermatozoa were obtained, no significant difference was observed in terms of inflammatory parameters such as NLR, MLR, PLR, SII and SIRI (p=0.254; p=0.268; p=0.067; p=0.177; p=0.158, respectively). CONCLUSION: Serum inflammatory markers, which can be easily obtained in routine clinical practice, are not sufficient to predict micro-TESE results. Keywords: azoospermia, infertility, inflammatory markers, microdissection testicular sperm extraction