A Comparison of Vitamin D Levels and Hip Fracture Severity in Elderly Patients With and Without Type 2 Diabetes Mellitus: A Retrospective Clinical Study

Our study confirmed the paradox that patients with T2DM had increased BMD compared to age-adjusted nondiabetic counterparts. The difference in hip fracture severity was not statistically significant. ALB levels were similar, with malnutrition prevalent in both groups, although diabetic patients with malnutrition are correlated with lower VD levels. VD levels were similar in both groups, but PTH levels were significantly higher in nondiabetics. The relationship between T2DM and PTH remains controversial and needs further investigation. Clinicians should note that low VD levels do not accompany elevated PTH in patients with diabetes, and elevated PTH may indicate poorly controlled T2DM. VD deficiency, hypoalbuminemia, and impaired glycemic control are interconnected issues in elderly patients with low-energy hip fractures.

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Journal
Cureus
Published
2025-04-01
DOI
https://doi.org/10.7759/cureus.81574
Citations
1
Primary Topic
Vitamin D Research Studies
Type
article
Field-Weighted Citation Impact
1.47
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article

A Comparison of Vitamin D Levels and Hip Fracture Severity in Elderly Patients With and Without Type 2 Diabetes Mellitus: A Retrospective Clinical Study

Ioannis Papaioannou, Γεωργία Πανταζίδου, Eleni Jelastopulu, Neoklis A. Georgopoulos et al.
1 citations
Cureus
Vitamin D Research Studies
1.47
article

A Comparison of Vitamin D Levels and Hip Fracture Severity in Elderly Patients With and Without Type 2 Diabetes Mellitus: A Retrospective Clinical Study

Ioannis Papaioannou, Γεωργία Πανταζίδου, Eleni Jelastopulu, Neoklis A. Georgopoulos, Zinon T. Kokkalis, Andreas Baikousis
article en
1 citations

Abstract

Our study confirmed the paradox that patients with T2DM had increased BMD compared to age-adjusted nondiabetic counterparts. The difference in hip fracture severity was not statistically significant. ALB levels were similar, with malnutrition prevalent in both groups, although diabetic patients with malnutrition are correlated with lower VD levels. VD levels were similar in both groups, but PTH levels were significantly higher in nondiabetics. The relationship between T2DM and PTH remains controversial and needs further investigation. Clinicians should note that low VD levels do not accompany elevated PTH in patients with diabetes, and elevated PTH may indicate poorly controlled T2DM. VD deficiency, hypoalbuminemia, and impaired glycemic control are interconnected issues in elderly patients with low-energy hip fractures.

CureusVol. 17(4)
General University Hospital of Patras (GR)
Openalex Percentile: Top 21%
Vitamin D Research Studies
1.47
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