Grouped multi-scale vision transformer for medical image segmentation

Medical image segmentation plays a pivotal role in clinical diagnosis and pathological research by delineating regions of interest within medical images. While early approaches based on Convolutional Neural Networks (CNNs) have achieved significant success, their limited receptive field constrains their ability to capture long-range dependencies. Recent advances in Vision Transformers (ViTs) have demonstrated remarkable improvements by leveraging self-attention mechanisms. However, existing ViT-based segmentation models often struggle to effectively capture multi-scale variations within a single attention layer, limiting their capacity to model complex anatomical structures. To address this limitation, we propose Grouped Multi-Scale Attention (GMSA), which enhances multi-scale feature representation by grouping channels and performing self-attention at different scales within a single layer. Additionally, we introduce Inter-Scale Attention (ISA) to facilitate cross-scale feature fusion, further improving segmentation performance. Extensive experiments on the Synapse, ACDC, and ISIC2018 datasets demonstrate the effectiveness of our model, achieving state-of-the-art results in medical image segmentation. Our code is available at: https://github.com/Chen2zheng/ScaleFormer .

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Publication Details

Journal
Scientific Reports
Published
2025-04-01
DOI
https://doi.org/10.1038/s41598-025-95361-8
Citations
5
Primary Topic
Advanced Neural Network Applications
Type
article
Field-Weighted Citation Impact
6.38

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article

Grouped multi-scale vision transformer for medical image segmentation

Zexuan Ji, Zheng Chen, Xiao Ma
5 citations
Scientific Reports
Advanced Neural Network Applications
6.38
article

Grouped multi-scale vision transformer for medical image segmentation

Zexuan Ji, Zheng Chen, Xiao Ma
article en
5 citations

Abstract

Medical image segmentation plays a pivotal role in clinical diagnosis and pathological research by delineating regions of interest within medical images. While early approaches based on Convolutional Neural Networks (CNNs) have achieved significant success, their limited receptive field constrains their ability to capture long-range dependencies. Recent advances in Vision Transformers (ViTs) have demonstrated remarkable improvements by leveraging self-attention mechanisms. However, existing ViT-based segmentation models often struggle to effectively capture multi-scale variations within a single attention layer, limiting their capacity to model complex anatomical structures. To address this limitation, we propose Grouped Multi-Scale Attention (GMSA), which enhances multi-scale feature representation by grouping channels and performing self-attention at different scales within a single layer. Additionally, we introduce Inter-Scale Attention (ISA) to facilitate cross-scale feature fusion, further improving segmentation performance. Extensive experiments on the Synapse, ACDC, and ISIC2018 datasets demonstrate the effectiveness of our model, achieving state-of-the-art results in medical image segmentation. Our code is available at: https://github.com/Chen2zheng/ScaleFormer .

Scientific ReportsVol. 15(1)
Nanjing University of Science and Technology (CN)
National Natural Science Foundation of China
Openalex Percentile: Top 4%
Advanced Neural Network Applications
6.38
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