Focal Hypertrichosis during Topical Tacrolimus Therapy for Vitiligo: A Case Report

We propose that the focal hypertrichosis was induced by tacrolimus. The hair growth-stimulating effects of tacrolimus have been established. It is reported that tacrolimus directly stimulates mouse whiskers in vitro and prolongs the anagen phase of hair growth when it is applied topically in mice. We believe that a greater awareness of this rare side effect of tacrolimus is warranted as tacrolimus is widely used in treating vitiligo.

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Publication Details

Journal
Case Reports in Dermatology
Published
2025-04-01
DOI
https://doi.org/10.1159/000545115
Primary Topic
Signaling Pathways in Disease
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article
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article

Focal Hypertrichosis during Topical Tacrolimus Therapy for Vitiligo: A Case Report

Huaxu Liu, Lingyu Mao, Xueping Yu, Yan Lin
1 links
Case Reports in Dermatology
Signaling Pathways in Disease
article

Focal Hypertrichosis during Topical Tacrolimus Therapy for Vitiligo: A Case Report

Huaxu Liu, Lingyu Mao, Xueping Yu, Yan Lin
article en

Abstract

We propose that the focal hypertrichosis was induced by tacrolimus. The hair growth-stimulating effects of tacrolimus have been established. It is reported that tacrolimus directly stimulates mouse whiskers in vitro and prolongs the anagen phase of hair growth when it is applied topically in mice. We believe that a greater awareness of this rare side effect of tacrolimus is warranted as tacrolimus is widely used in treating vitiligo.

Case Reports in DermatologyVol. 17(1)
Shandong Provincial Institute of Dermatology and Venereology (CN), Shandong First Medical University (CN)
Good health and well-being
Openalex Percentile: Top 94%
Signaling Pathways in Disease
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