School-age outcomes among IVF and ICSI-conceived children: a causal inference analysis using linked population-wide data
Our findings suggest that the use of ICSI in IVF cycles without severe male factor infertility does not increase the risk of early childhood developmental vulnerability among children in their first year of school. These findings provide important reassurance for current and prospective parents and clinicians alike.
Authors
- Susan Walker (ORCID: https://orcid.org/0000-0001-9075-4655)
- Tiki Osianlis (ORCID: https://orcid.org/0009-0002-3783-4095)
- Roxanne Hastie (ORCID: https://orcid.org/0000-0002-4342-1943)
- Jeanie L.Y. Cheong (ORCID: https://orcid.org/0000-0001-5901-0455)
- Amber L. Kennedy (ORCID: https://orcid.org/0000-0002-7663-8102)
- Aleah Kink (ORCID: https://orcid.org/0000-0002-6034-2833)
- Lyle C. Gurrin (ORCID: https://orcid.org/0000-0001-7052-1969)
- John McBain (ORCID: https://orcid.org/0000-0002-8677-794X)
- Stephen Tong (ORCID: https://orcid.org/0000-0002-2319-0586)
- Anthea Lindquist (ORCID: https://orcid.org/0000-0002-8662-5188)
- Mark P. Green (ORCID: https://orcid.org/0000-0002-6076-9781)
- Richard John Hiscock (ORCID: https://orcid.org/0000-0001-5375-041X)
- Jon Quach (ORCID: https://orcid.org/0000-0002-3055-3082)
- Beverley Vollenhoven (ORCID: https://orcid.org/0000-0002-8756-3994)
- David Wilkinson (ORCID: https://orcid.org/0000-0001-5165-8230)
- Susan P. Baohm
- Jessica Atkinson (ORCID: https://orcid.org/0000-0002-6604-7456)
- Catharyn Stern
- Franca Agresta
Institutions
- Royal Women's Hospital (AU)
- The University of Melbourne (AU)
- BirdLife Australia (AU)
- Mercy Hospital for Women (AU)
- Victorian Curriculum and Assessment Authority (AU)
- Myer Foundation (AU)
- Monash Health (AU)
- Monash IVF (AU)
- Murdoch Children's Research Institute (AU)
- Melbourne Health (AU)
- Monash University (AU)
Publication Details
- Journal
- BMC Medicine
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1186/s12916-025-03963-w
- Citations
- 2
- Primary Topic
- Assisted Reproductive Technology and Twin Pregnancy
- Type
- article
- Field-Weighted Citation Impact
- 6.99
Funders
- Australian Government
- Ferring Pharmaceuticals