Optical coherence tomography for label-free detection and characterization of methicillin-resistant S. aureus biofilms
The proposed rapid noninvasive detection/quantification of MRSA biofilms on metal surfaces and delineation of their complex network of pores opens new venues for label-free MRSA detection in preclinical models of trauma surgery, expansion to other bacterial strains, and further clinical translation.
Authors
- I. Alex Vitkin (ORCID: https://orcid.org/0000-0001-5495-8888)
- Valentin Demidov (ORCID: https://orcid.org/0000-0002-0960-3858)
- Ida Leah Gitajn (ORCID: https://orcid.org/0000-0001-8649-7385)
- Jonathan T. Elliott (ORCID: https://orcid.org/0000-0002-8485-0234)
- Natalia Demidova (ORCID: https://orcid.org/0000-0002-6048-5316)
- Jason R. Gunn
Institutions
- University of Toronto (CA)
- Dartmouth Psychiatric Research Center (US)
- Dartmouth Health (US)
Publication Details
- Journal
- Journal of Biomedical Optics
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1117/1.jbo.30.4.046003
- Citations
- 1
- Primary Topic
- Optical Coherence Tomography Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.67
Funders
- Hitchcock Foundation
- Dartmouth Cancer Center
- National Institutes of Health