A video summary of the HIMALAYA study PLSP: Tremelimumab and Durvalumab for Unresectable Hepatocellular Carcinoma

The phase III study, HIMALAYA, compared treatment with tremelimumab plus durvalumab (STRIDE regimen) or durvalumab alone versus sorafenib in participants with unresectable hepatocellular carcinoma (HCC). Participants who took STRIDE lived longer and were less likely to experience side effects related to treatment than participants who took sorafenib. Overall, the results of this study showed that STRIDE was more effective than sorafenib for people with unresectable HCC.

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Publication Details

Journal
Video Journal of Biomedicine
Published
2025-04-01
DOI
https://doi.org/10.1080/vjbm-2023-0016
Primary Topic
Hepatocellular Carcinoma Treatment and Prognosis
Type
article
Field-Weighted Citation Impact
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article

A video summary of the HIMALAYA study PLSP: Tremelimumab and Durvalumab for Unresectable Hepatocellular Carcinoma

Ghassan K. Abou‐Alfa
2 links
Video Journal of Biomedicine
Hepatocellular Carcinoma Treatment and Prognosis
article

A video summary of the HIMALAYA study PLSP: Tremelimumab and Durvalumab for Unresectable Hepatocellular Carcinoma

Ghassan K. Abou‐Alfa
article en

Abstract

The phase III study, HIMALAYA, compared treatment with tremelimumab plus durvalumab (STRIDE regimen) or durvalumab alone versus sorafenib in participants with unresectable hepatocellular carcinoma (HCC). Participants who took STRIDE lived longer and were less likely to experience side effects related to treatment than participants who took sorafenib. Overall, the results of this study showed that STRIDE was more effective than sorafenib for people with unresectable HCC.

Video Journal of Biomedicine
Memorial Sloan Kettering Cancer Center (US), Cornell University (US)
Openalex Percentile: Top 91%
Hepatocellular Carcinoma Treatment and Prognosis
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