Prospective Validation of ATA Risk Score for Papillary Thyroid Microcarcinoma: An ITCO Real-World Study
Our study confirms the favorable initial outcome of microPTC in a large series. We demonstrate that the ATA risk classification is reliable in predicting biochemical and structural persistence in patients with microPTC. Distant metastases, although rare, remain the best predictor of structural persistence at 1-year follow-up. These findings underscore the importance of tailored management strategies based on comprehensive risk stratification, rather than solely on tumor size.
Authors
- Silvia D'Elia
- Tommaso Porcelli (ORCID: https://orcid.org/0000-0002-6162-5819)
- Efisio Puxeddu (ORCID: https://orcid.org/0000-0001-9611-6216)
- Giulia Brigante (ORCID: https://orcid.org/0000-0001-8426-4502)
- Ilaria Stramazzo (ORCID: https://orcid.org/0000-0001-7870-1729)
- Simone De Leo (ORCID: https://orcid.org/0000-0002-1534-8216)
- Nicoletta Rolli
- Andrea Lania (ORCID: https://orcid.org/0000-0002-5380-2141)
- Alice Nervo (ORCID: https://orcid.org/0000-0002-9227-2075)
- Loredana Pagano (ORCID: https://orcid.org/0000-0002-9125-4721)
- Alessandra Colapinto
- Giorgio Grani (ORCID: https://orcid.org/0000-0002-0388-1283)
- Umberto Ferraro Petrillo (ORCID: https://orcid.org/0000-0002-4308-5126)
- Salvatore Monti (ORCID: https://orcid.org/0000-0001-5861-5727)
- Camilla Virili (ORCID: https://orcid.org/0000-0002-4973-1950)
- Andrea Repaci (ORCID: https://orcid.org/0000-0002-8061-8147)
- Francesco Dondi (ORCID: https://orcid.org/0000-0003-4839-9033)
- Sébastiano Filetti (ORCID: https://orcid.org/0000-0001-8570-6448)
- Francesca Retta (ORCID: https://orcid.org/0000-0002-4107-4685)
- Cristina Clausi
- Maria Rosaria Ambrosio (ORCID: https://orcid.org/0000-0002-7911-9770)
- Chiara Mele (ORCID: https://orcid.org/0000-0003-2880-9373)
- Nicola Salituro
- Clotilde Sparano (ORCID: https://orcid.org/0000-0002-3766-4682)
- Simona Censi (ORCID: https://orcid.org/0000-0001-6946-9673)
- Mario Rotondi (ORCID: https://orcid.org/0000-0001-6464-2334)
- Dario Tumino (ORCID: https://orcid.org/0000-0003-1021-6692)
- Bruno Madeo (ORCID: https://orcid.org/0000-0003-2881-982X)
- Maria Chiara Zatelli (ORCID: https://orcid.org/0000-0001-8408-7796)
- Michela Massa
- Virginia Adornato
- Giovanna Spiazzi
- Cosimo Durante (ORCID: https://orcid.org/0000-0002-1791-5915)
- Laura Fugazzola (ORCID: https://orcid.org/0000-0001-5372-0982)
- Maurilio Deandrea (ORCID: https://orcid.org/0000-0001-9217-8815)
- Poupak Fallahi (ORCID: https://orcid.org/0000-0002-5455-4186)
- Erica Solaroli
- Graziano Ceresini (ORCID: https://orcid.org/0000-0003-3347-4096)
- Maria Grazia Chiofalo (ORCID: https://orcid.org/0000-0002-1519-1378)
- Andrea Palermo
- Flavia Magri (ORCID: https://orcid.org/0000-0003-4846-9847)
- Alfonso Sagnella (ORCID: https://orcid.org/0000-0003-2247-9027)
- Luisa Petrone (ORCID: https://orcid.org/0000-0002-2167-8844)
- Antonio Brunetti (ORCID: https://orcid.org/0000-0003-1533-8779)
- Francesco Felicetti (ORCID: https://orcid.org/0000-0002-6642-8750)
- Mattia Rossi (ORCID: https://orcid.org/0000-0002-8792-5334)
- Francesco Bertagna (ORCID: https://orcid.org/0000-0003-2980-5964)
- Cristina Basso (ORCID: https://orcid.org/0000-0002-0195-9753)
- Marco Alfò (ORCID: https://orcid.org/0000-0001-7651-6052)
- Maria Giulia Santaguida (ORCID: https://orcid.org/0000-0001-5311-4886)
- Andrea Liverani
- Rocco Bruno (ORCID: https://orcid.org/0009-0008-8080-4952)
- Umberto Crocetti
- Giulia Di Dalmazi (ORCID: https://orcid.org/0000-0001-9213-8039)
- Silvia Morelli
- Alessandro Piovesan (ORCID: https://orcid.org/0000-0002-8188-8894)
- Matteo Trevisan (ORCID: https://orcid.org/0000-0001-5913-1337)
- Antonella Carbone (ORCID: https://orcid.org/0009-0006-2179-0525)
- Edoardo Talpacci
- Roberto Castello
- Michela Marina
- Marco Zavattaro
Institutions
- University of Siena (IT)
- University of Pisa (IT)
- University of Verona (IT)
- University of Modena and Reggio Emilia (IT)
- Università degli Studi del Piemonte Orientale “Amedeo Avogadro” (IT)
- University of Parma (IT)
- Humanitas University (IT)
- University of Padua (IT)
- University of Ferrara (IT)
- University of Pavia (IT)
- University of Perugia (IT)
- Casa Sollievo della Sofferenza (IT)
- Brescia University (US)
- Magna Graecia University (IT)
- University of Catania (IT)
- University of Chieti-Pescara (IT)
- European Society for Sexual Medicine (IT)
- Istituti Clinici Scientifici Maugeri (IT)
- Azienda Ospedaliera Universitaria Integrata Verona (IT)
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (IT)
- Department of Medical Sciences (RU)
- University Hospitals Parma Medical Center (US)
- Azienda USL di Bologna (IT)
- Azienda Ospedaliera Sant'Andrea (IT)
- Department of Medical Sciences (BY)
- A. O. Ordine Mauriziano di Torino (IT)
- IRCCS Istituto Auxologico Italiano (IT)
- Ospedale Regina Apostolorum (IT)
- Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale" (IT)
- Campus Bio Medico University Hospital (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Mater Hospital (GB)
- IRCCS Humanitas Research Hospital (IT)
- University of Florence (IT)
- University of Turin (IT)
- University of Naples Federico II (IT)
- University of Brescia (IT)
- Sapienza University of Rome (IT)
- University of Bologna (IT)
Publication Details
- Journal
- The Journal of Clinical Endocrinology & Metabolism
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1210/clinem/dgaf190
- Citations
- 1
- Primary Topic
- Thyroid Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.29
Funders
- Ministero della Salute