Dilated cardiomyopathy - guidelines for personalization of care

The term dilated cardiomyopathy (DCM) refers to a family of diseases characterized by complex interactions between environment and genetic predisposition. Diagnostic tools such as cardiac magnetic resonance imaging should be systematically implemented in clinical practice to define the etiological cause and undertake a specific treatment. We present the case of a young man with DCM and severe left ventricular dysfunction. The patient has a family history of sudden cardiac death (SCD). He is affected by a psychiatric pathology and has a history of alcohol and drug addiction. Many diagnostic hypotheses have been considered for etiological research. The use of a wearable defibrillator to temporarily protect the patient from SCD risk pending the completion of the diagnostic path to establish DCM etiology and the implementation of optimal medical therapy was considered. However, because of the underlying psychiatric pathology and the possibility of poor adherence to the maintenance of the wearable device, the patients would not have been sufficiently protected. Due to the young age of the patient, it was decided to make a personalized therapeutic choice, and he underwent implantation of a subcutaneous defibrillator.

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Journal
Monaldi Archives for Chest Disease
Published
2025-04-01
DOI
https://doi.org/10.4081/monaldi.2025.3173
Primary Topic
Cardiovascular Function and Risk Factors
Type
article
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article

Dilated cardiomyopathy - guidelines for personalization of care

Alfredo Macchiusi, Stefania Angela Di Fusco, G. Marino, Carlo Pignalberi et al.
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Monaldi Archives for Chest Disease
Cardiovascular Function and Risk Factors
article

Dilated cardiomyopathy - guidelines for personalization of care

Alfredo Macchiusi, Stefania Angela Di Fusco, G. Marino, Carlo Pignalberi, Furio Colivicchi, Antonella Spinelli
article en

Abstract

The term dilated cardiomyopathy (DCM) refers to a family of diseases characterized by complex interactions between environment and genetic predisposition. Diagnostic tools such as cardiac magnetic resonance imaging should be systematically implemented in clinical practice to define the etiological cause and undertake a specific treatment. We present the case of a young man with DCM and severe left ventricular dysfunction. The patient has a family history of sudden cardiac death (SCD). He is affected by a psychiatric pathology and has a history of alcohol and drug addiction. Many diagnostic hypotheses have been considered for etiological research. The use of a wearable defibrillator to temporarily protect the patient from SCD risk pending the completion of the diagnostic path to establish DCM etiology and the implementation of optimal medical therapy was considered. However, because of the underlying psychiatric pathology and the possibility of poor adherence to the maintenance of the wearable device, the patients would not have been sufficiently protected. Due to the young age of the patient, it was decided to make a personalized therapeutic choice, and he underwent implantation of a subcutaneous defibrillator.

Monaldi Archives for Chest Disease
Ospedale San Filippo Neri (IT)
No poverty, Good health and well-being
Openalex Percentile: Top 89%
Cardiovascular Function and Risk Factors
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Dilated cardiomyopathy - guidelines for personalization of care — Alfredo Macchiusi, Stefania Angela Di Fusco, et al. · Monaldi Archives for Chest Disease (2025) | TGRS Research Map | TGRS