Causal Characteristics of Immune Cells Associated with Aortic Dissection: A Mendelian Randomisation Analysis

This study suggests potential causal roles for specific immune cell traits in AD pathogenesis, although these findings should be interpreted with caution due to study limitations. The identified immune cell types and associated eQTL genes offer promising targets for clinical risk stratification and therapeutic interventions. Future research should focus on translating these findings into practical strategies for patient care.

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Publication Details

Journal
European Cardiology Review
Published
2025-04-01
DOI
https://doi.org/10.15420/ecr.2024.44
Citations
4
Primary Topic
Cancer-related molecular mechanisms research
Type
article
Field-Weighted Citation Impact
3.75
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article

Causal Characteristics of Immune Cells Associated with Aortic Dissection: A Mendelian Randomisation Analysis

Ying-wu Liu, Lei Huang, Tian-le Li, Lihong Wang et al.
4 citations
European Cardiology Review
Cancer-related molecular mechanisms research
3.75
article

Causal Characteristics of Immune Cells Associated with Aortic Dissection: A Mendelian Randomisation Analysis

Ying-wu Liu, Lei Huang, Tian-le Li, Lihong Wang, Jianlong Wang, M.J. Fu
article en
4 citations

Abstract

This study suggests potential causal roles for specific immune cell traits in AD pathogenesis, although these findings should be interpreted with caution due to study limitations. The identified immune cell types and associated eQTL genes offer promising targets for clinical risk stratification and therapeutic interventions. Future research should focus on translating these findings into practical strategies for patient care.

European Cardiology ReviewVol. 20
Tianjin University (CN), Tianjin Third Central Hospital (CN), Tianjin Hospital (CN), Tianjin Medical University (CN)
Good health and well-being
Openalex Percentile: Top 7%
Cancer-related molecular mechanisms research
3.75
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