Unexpected effects of treating insulin-resistant obese women with high-dose D-chiro-inositol: opening Pandora’s box
The study strengthens the evidence regarding the metabolic benefits of the hypocaloric Mediterranean diet, independent from the association with DCI, on women with insulin resistance and excess weight, while also acknowledging the complex hormonal impact of high-dose DCI supplementation for medium-to-long periods.
Authors
- Sabrina Basciani (ORCID: https://orcid.org/0000-0002-7201-3738)
- Lucio Gnessi (ORCID: https://orcid.org/0000-0001-8217-2372)
- Maurizio Nordio (ORCID: https://orcid.org/0000-0001-6820-2512)
- Maria Letizia Spizzichini
Institutions
- Sapienza University of Rome (IT)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-04-01
- DOI
- https://doi.org/10.3389/fendo.2025.1399308
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00