[CuI(PPh<sub>3</sub>)<sub>3</sub>]‐Mediated Arylation of 1,2,3‐Triazoles

Abstract The arylation of 1,4‐disubstituted triazoles with [CuI(PPh 3 ) 3 ] is reported. The reactions were carried out in relatively concentrated solutions of hot DMF in the presence of air and moisture. These conditions were suitable for a range of substrates, specifically triazoles containing a pyridyl group, which are of interest in diverse applications such as ancillary ligands or bioactive compounds.

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Publication Details

Journal
ChemCatChem
Published
2025-04-01
DOI
https://doi.org/10.1002/cctc.202500111
Citations
1
Primary Topic
Catalytic Cross-Coupling Reactions
Type
article
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article

[CuI(PPh3)3]‐Mediated Arylation of 1,2,3‐Triazoles

Steven Lal, Silvia Díez‐González, Jingjing Qian, Raul Pacheco Muino et al.
1 citations
ChemCatChem
Catalytic Cross-Coupling Reactions
article

[CuI(PPh3)3]‐Mediated Arylation of 1,2,3‐Triazoles

Steven Lal, Silvia Díez‐González, Jingjing Qian, Raul Pacheco Muino, Vera Kleene, Matthew Faulkes
article en
1 citations

Abstract

Abstract The arylation of 1,4‐disubstituted triazoles with [CuI(PPh 3 ) 3 ] is reported. The reactions were carried out in relatively concentrated solutions of hot DMF in the presence of air and moisture. These conditions were suitable for a range of substrates, specifically triazoles containing a pyridyl group, which are of interest in diverse applications such as ancillary ligands or bioactive compounds.

ChemCatChemVol. 17(11)
AstraZeneca (United Kingdom) (GB), AstraZeneca (Singapore) (SG), AstraZeneca (Poland) (PL), Imperial College London (GB)
Openalex Percentile: Top 95%
Catalytic Cross-Coupling Reactions
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