A mechanochemical addition/reduction cascade process for the synthesis of dual stereocentered chiral δ-hydroxysulfones
A mechanochemical method for dual asymmetric catalysis is developed, which prevents mutual deactivation between chiral squaramide and ruthenium species. This enables an addition/reduction cascade process for the synthesis of chiral δ-hydroxysulfones.
Authors
- Guohua Liu (ORCID: https://orcid.org/0000-0001-8407-3095)
- Yongjin Zhang (ORCID: https://orcid.org/0000-0002-4058-0658)
- Tianqi Xu (ORCID: https://orcid.org/0000-0002-9817-7597)
- Yanwen Gong (ORCID: https://orcid.org/0000-0002-5046-6250)
- Kun Zhang (ORCID: https://orcid.org/0000-0003-3892-3380)
- Bin Jiang (ORCID: https://orcid.org/0000-0002-4858-0505)
- Donghua He (ORCID: https://orcid.org/0000-0002-9268-8732)
Institutions
- Shanghai Normal University (CN)
Publication Details
- Journal
- Organic Chemistry Frontiers
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d4qo02158d
- Citations
- 1
- Primary Topic
- Axial and Atropisomeric Chirality Synthesis
- Type
- article
- Field-Weighted Citation Impact
- 0.94