Local estradiol deposition in a rat rotator cuff repair model: proof of concept
This study demonstrates that a PCL implant is capable of sustained release of estradiol over 6 weeks and concentrates estradiol locally. Local deposition of estradiol increases local BMD rapidly.
Authors
- James M. Hotaling (ORCID: https://orcid.org/0000-0002-4401-4565)
- Matthew Honeggar
- Michael J. Jurynec (ORCID: https://orcid.org/0000-0003-2702-9164)
- Benjamin R. Emery (ORCID: https://orcid.org/0000-0001-5086-6089)
- Peter N. Chalmers (ORCID: https://orcid.org/0000-0002-1275-0285)
- Robert Z. Tashjian (ORCID: https://orcid.org/0000-0003-4112-0423)
- Antonio C. Zelada
- A Hickey (ORCID: https://orcid.org/0009-0001-6815-5813)
- T Wade Fallin
Institutions
- University of Utah (US)
Publication Details
- Journal
- JSES International
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1016/j.jseint.2025.03.004
- Primary Topic
- Shoulder Injury and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00