Retrospective analysis of the follow up PET/CT studies using 18F-fluorodeoxyglucose in patients with breast cancer

Depending on the morphological structure of the malignant process, the stage of the disease, and the presence of concomitant diseases, the treatment tactics for patients with cancer are determined. The correct choice of treatment tactics determines the quality of life and survival of patients.The use of positron emission tomography combined with computed tomography for breast cancer allows to accurately and reliably characterize the primary tumor, the presence and location of metastatic lesions, as well as evaluate the metabolic activity in them, which allows one to evaluate the effectiveness of treatment.We conducted a retrospective analysis of repeated studies of positron emission tomography combined with computed tomography using 18F-2-fluoro-2-deoxy-D-glucose in patients with breast cancer.The purpose of the study was to determine the correlation of the dynamics of the disease with the histological structure of the tumor, the primary staging of the disease, and the treatment performed.Data from studies of positron emission tomography combined with computed tomography using 18F-2-fluoro-2-deoxy-D-glucose in patients with breast cancer for the period 2010-2020 were used. To select patients, we used the following criteria known from the medical documentation provided to us: histological structure of the tumor, TNM staging, and treatment performed.The majority of patients showed stable remission of the disease (60%), and in the vast majority of cases the histological picture was represented by infiltrating carcinomas (90%). Disease progression was detected in 28.4% of cases. There was a preference for positron emission tomography combined with computed tomography using 18F-2-fluoro-2-deoxy-D-glucose in referral of the patients with T2 stage of the disease.Keywords: positron emission tomography combined with computed tomography, breast cancer, disease dynamics.