Dupilumab for Chronic Rhinosinusitis with Primary Nasal Polyps: a Case Report and Literature Review
By specifically inhibiting the IL-4 and IL-13 pathways, dupilumab can significantly improve sinusitis symptoms and olfactory function in CRSwNP patients, and significantly reduce the number of acute exacerbations of chronic rhinosinusitis, the range of sinusitis lesions, and the level of systemic corticosteroids.
Authors
- Rao Fu (ORCID: https://orcid.org/0000-0001-8619-4616)
- Mingrui Deng (ORCID: https://orcid.org/0009-0008-2492-2161)
- LV Mei
- Feng Ya
Institutions
- Dalian Medical University (CN)
- First Affiliated Hospital of Dalian Medical University (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-04-01
- DOI
- https://doi.org/10.2147/jir.s513138
- Primary Topic
- Sinusitis and nasal conditions
- Type
- article
- Field-Weighted Citation Impact
- 0.00