Downregulation of FASN in granulosa cells and its impact on ovulatory dysfunction in PCOS
Our results provide new insights into PCOS pathogenesis and suggest that FASN could be a promising target for treating abnormal steroid hormone production and impaired ovulation in PCOS.
Authors
- Liang Chen (ORCID: https://orcid.org/0000-0001-6644-477X)
- Tiancheng Wu (ORCID: https://orcid.org/0009-0006-7383-178X)
- Mei Wang (ORCID: https://orcid.org/0000-0002-4740-3320)
- Ming Zhang (ORCID: https://orcid.org/0009-0009-7742-3128)
- Yating Li (ORCID: https://orcid.org/0000-0002-7768-7264)
- Zhaoping Tan
- Lili Sun
Institutions
- Wuhan University (CN)
- Zhongnan Hospital of Wuhan University (CN)
Publication Details
- Journal
- Journal of Ovarian Research
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1186/s13048-025-01645-y
- Citations
- 1
- Primary Topic
- Ovarian function and disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.70
Funders
- Natural Science Foundation of Hubei Province