Functional and Structural Network Alterations in HIV-Associated Asymptomatic Neurocognitive Disorders: Evidence for Functional Disruptions Preceding Structural Changes
Functional network reorganization and enhanced functional-structural coupling may reflect early synaptic and dendritic damage in persons with ANI, serving as potential early warning signals for HAND progression. These findings provide sensitive biomarkers and valuable perspectives for early diagnosis and intervention.
Authors
- Fuchun Wang (ORCID: https://orcid.org/0000-0002-8043-2158)
- Wenru Gong
- Hui Li
- Hong Hu
- Zhongkai Zhou (ORCID: https://orcid.org/0009-0002-1923-0394)
- Hongjun Li (ORCID: https://orcid.org/0000-0002-6994-4160)
- Wei Wang (ORCID: https://orcid.org/0000-0001-6183-0559)
- Fan Xu (ORCID: https://orcid.org/0009-0008-5666-8401)
Institutions
- Harbin Medical University (CN)
- Capital Medical University (CN)
- Beijing YouAn Hospital (CN)
- First Affiliated Hospital of Harbin Medical University (CN)
Publication Details
- Journal
- Neuropsychiatric Disease and Treatment
- Published
- 2025-04-01
- DOI
- https://doi.org/10.2147/ndt.s508747
- Citations
- 2
- Primary Topic
- HIV Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.07