Role of saponins in the prevention and treatment of liver fibrosis

This paper aims to investigate the mechanism of saponins in the prevention and treatment of liver fibrosis. Based on a comprehensive analysis of relevant literature, the structural characteristics, distribution and main types of saponins were described, and the research progress of saponins in inhibiting lipid peroxidation, reducing hepatic stellate cell activation and proliferation, inhibiting immune inflammatory response, regulating mitochondrial function and other related mechanisms were analyzed in detail. Studies have shown that saponins have multi-target and multi-pathway anti-fibrosis effects, which provides a theoretical basis for their application in the treatment of liver fibrosis.

Publication Details

Journal
International Journal of Frontiers in Medicine
Published
2025-01-01
DOI
https://doi.org/10.25236/ijfm.2025.070110
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Role of saponins in the prevention and treatment of liver fibrosis

International Journal of Frontiers in Medicine
Liver Disease Diagnosis and Treatment
article

Role of saponins in the prevention and treatment of liver fibrosis

article en

Abstract

This paper aims to investigate the mechanism of saponins in the prevention and treatment of liver fibrosis. Based on a comprehensive analysis of relevant literature, the structural characteristics, distribution and main types of saponins were described, and the research progress of saponins in inhibiting lipid peroxidation, reducing hepatic stellate cell activation and proliferation, inhibiting immune inflammatory response, regulating mitochondrial function and other related mechanisms were analyzed in detail. Studies have shown that saponins have multi-target and multi-pathway anti-fibrosis effects, which provides a theoretical basis for their application in the treatment of liver fibrosis.

International Journal of Frontiers in MedicineVol. 7(1)
Good health and well-being
Openalex Percentile: Top 91%
Liver Disease Diagnosis and Treatment
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Role of saponins in the prevention and treatment of liver fibrosis · International Journal of Frontiers in Medicine (2025) | TGRS Research Map | TGRS