Rhein-induced apoptosis in colorectal cancer cell lines: A mechanistic study of the myeloid differentiation primary response gene 88/toll-like receptor 4/nuclear factor kappa-B signaling pathway
Rhein appears to promote apoptosis in CRC cells through the MYD88/TLR4/NF-κB signaling pathway, thus inhibiting tumor initiation and progression.
Authors
- Longfei Hu (ORCID: https://orcid.org/0000-0002-6714-9235)
- Zhengang Zhao
- Xiaolan Zhang (ORCID: https://orcid.org/0000-0002-7047-3634)
- Xichen Zheng (ORCID: https://orcid.org/0000-0002-9868-4396)
- Lei Mao (ORCID: https://orcid.org/0000-0002-8857-621X)
- Xixi Chen (ORCID: https://orcid.org/0000-0002-0405-8889)
Institutions
- Wenzhou Medical University (CN)
- Ruian People's Hospital (CN)
Publication Details
- Journal
- CytoJournal
- Published
- 2025-04-01
- DOI
- https://doi.org/10.25259/cytojournal_257_2024
- Primary Topic
- Genomics, phytochemicals, and oxidative stress
- Type
- article
- Field-Weighted Citation Impact
- 0.00