Zinc finger and broad-complex, tramtrack, and bric-a-brac domain containing 16 silencing attenuates bleomycin-induced pulmonary fibrosis in mice through inhibition of the phosphoinositide 3-kinase/protein kinase B/mammalian target of rapamycin pathwa

This study identified Zbtb16 as a key regulator of PF progression, mediating its effects through the PAmT-P. Zbtb16 silencing alleviated fibrosis and inflammation <i>in vivo</i> and <i>in vitro</i>, providing a promising target for therapeutic intervention in PF.

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Publication Details

Journal
CytoJournal
Published
2025-04-01
DOI
https://doi.org/10.25259/cytojournal_223_2024
Citations
1
Primary Topic
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Type
article
Field-Weighted Citation Impact
1.52
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article

Zinc finger and broad-complex, tramtrack, and bric-a-brac domain containing 16 silencing attenuates bleomycin-induced pulmonary fibrosis in mice through inhibition of the phosphoinositide 3-kinase/protein kinase B/mammalian target of rapamycin pathwa

Xiaoyun Wen, Liefeng Wang, Yingjie Jiang, Xiansong Fang et al.
1 citations
CytoJournal
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
1.52
article

Zinc finger and broad-complex, tramtrack, and bric-a-brac domain containing 16 silencing attenuates bleomycin-induced pulmonary fibrosis in mice through inhibition of the phosphoinositide 3-kinase/protein kinase B/mammalian target of rapamycin pathwa

Xiaoyun Wen, Liefeng Wang, Yingjie Jiang, Xiansong Fang, Liang Zhou
article en
1 citations

Abstract

This study identified Zbtb16 as a key regulator of PF progression, mediating its effects through the PAmT-P. Zbtb16 silencing alleviated fibrosis and inflammation <i>in vivo</i> and <i>in vitro</i>, providing a promising target for therapeutic intervention in PF.

CytoJournalVol. 22
Gannan Medical University (CN), First Affiliated Hospital of Gannan Medical University (CN), China Medical University (CN)
Openalex Percentile: Top 20%
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
1.52
DOIOpen Access PDFOpenAlex
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Zinc finger and broad-complex, tramtrack, and bric-a-brac domain containing 16 silencing attenuates bleomycin-induced pulmonary fibrosis in mice through inhibition of the phosphoinositide 3-kinase/protein kinase B/mammalian target of rapamycin pathwa — Xiaoyun Wen, Liefeng Wang, et al. · CytoJournal (2025) | TGRS Research Map | TGRS