Calcifying epithelial odontogenic tumor: a case series from South America
Objective: To describe a case series of calcifying epithelial odontogenic tumor (CEOT) from South America. Methods: This study analyzed cases from Brazil (n=7), Venezuela (n=4), and Colombia (n=1), providing their clinicopathologic, radiographic, and treatment characteristics. Results: The series comprised seven (58.3%) females and five (41.7%) males, with a mean age at diagnosis of 33.4 years (range: 19–61). Clinically, 66.7% of patients presented with swelling, and the duration of the lesions ranged from 24 to 120 months. The mandible was involved in 91.7% (n=11) of cases, predominantly in the posterior region (83.4%). Radiographically, 83.4% of lesions were expansive, 75% displayed mixed density, 58.4% were associated with an impacted tooth, and 50% showed root resorption. The median lesion size was 45 mm. Histopathologically, 10 (83.3%) cases were classified as “classic” CEOT, while two (16.7%) were identified as the clear-cell variant. Curettage was performed in 50% of cases and surgical removal (en bloc) in 33.3%. No recurrences were observed in nine (81.8%) cases over a median follow-up of 36 months. Conclusion: These findings align with existing literature, highlighting a predominance of young adult females who often present with asymptomatic swelling. The importance of vigilant long-term follow-up post-treatment is emphasized.
Authors
- José Alcides Almeida de Arruda (ORCID: https://orcid.org/0000-0002-6599-3950)
- Isabella Bittencourt do Valle (ORCID: https://orcid.org/0000-0002-3221-3057)
- Israel Leal Cavalcante (ORCID: https://orcid.org/0000-0002-0794-4106)
- Mariana Villarroel‐Dorrego (ORCID: https://orcid.org/0000-0002-0596-1527)
- José Victor Lemos Ventura (ORCID: https://orcid.org/0009-0004-5719-2565)
- Jefferson R. Tenório (ORCID: https://orcid.org/0000-0002-6986-9148)
- Claudia Patricia Peña‐Vega
- Bruno Augusto Benevenuto de Andrade (ORCID: https://orcid.org/0000-0002-3259-606X)
- ROGERIO DE OLIVEIRA GONDAK (ORCID: https://orcid.org/0000-0001-7547-660X)
- Maria Eduarda Zeraik Barreto (ORCID: https://orcid.org/0000-0002-9009-5757)
- José Ricardo Dias Pereira (ORCID: https://orcid.org/0009-0007-7244-7628)
- Gerhilde Callou Sampaio (ORCID: https://orcid.org/0000-0001-8437-471X)
- Ricardo Luiz Cavalcanti de Albuquerque Júnior (ORCID: https://orcid.org/0000-0003-4444-7632)
- Kallana Mezzomo Faccin (ORCID: https://orcid.org/0009-0000-9073-3301)
- Juan Pablo Rodríguez‐Mora (ORCID: https://orcid.org/0009-0009-3198-1861)
- Alejandra Rojas-Ponte
Institutions
- Universidade Federal do Rio de Janeiro (BR)
- Universidade Federal de Pernambuco (BR)
- Universidade de Fortaleza (BR)
- Universidad Nacional de Colombia (CO)
- Universidade Federal de Santa Catarina (BR)
- Fundación Universitaria Sanitas (CO)
- Universidade Federal do Espírito Santo (BR)
- Universidade de Pernambuco (BR)
- Universidad Central de Venezuela (VE)
Publication Details
- Journal
- JORDI - Journal of Oral Diagnosis
- Published
- 2025-03-28
- DOI
- https://doi.org/10.5327/2525-5711.286
- Citations
- 1
- Primary Topic
- Oral and Maxillofacial Pathology
- Type
- article
- Field-Weighted Citation Impact
- 1.79