Misoprostol (9E)-Oxime
With the goal of searching for new more chemically stable analogues (prodrugs), isomeric misoprostol (9E/Z)-oximes and individual 11α-acetoxy (9E)-O-acetyloxime derivative have been synthesized and characterized. The ratio of the E and Z oximes has been estimated at 10:1 on the basis of the oxime OH signal intensities in the 1H NMR spectrum.
Authors
- Н. С. Востриков (ORCID: https://orcid.org/0000-0003-1782-8675)
- Airat M. Gimazetdinov (ORCID: https://orcid.org/0000-0002-8539-3442)
- V. V. Zagitov (ORCID: https://orcid.org/0000-0002-0216-379X)
- Н. К. Селезнева (ORCID: https://orcid.org/0000-0002-9917-1912)
- M. S. Miftakhov (ORCID: https://orcid.org/0000-0002-0269-7484)
Institutions
- Ufa Institute of Chemistry (RU)
Publication Details
- Journal
- Russian Journal of Organic Chemistry
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1134/s1070428024604680
- Primary Topic
- Antiplatelet Therapy and Cardiovascular Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00