A computational DNA methylation method to remove contaminated DNA from spent embryo culture medium for noninvasive preimplantation genetic testing

This study was supported by grants from the Beijing Natural Science Foundation (7232203), the National Key R&D Program of China (2023YFC2705600, 2023YFC2705602), the National Natural Science Foundation of China (82301889, 82371706), the Key Clinical Projects of Peking University Third Hospital (BYSYZD2022029), the Young Elite Scientists Sponsorship Program by CAST (2023QNRC001), the Peking University Medicine Sailing Program for Young Scholars' Scientific & Technological Innovation (BMU2023YFJHPY001) and the special fund of the National Clinical Key Specialty Construction Program, P. R. China (2023). We thank support from the High Performance Computing Platform of the Centre for Life Sciences (Peking University) and Open Research Fund of the National Centre for Protein Sciences at Peking University in Beijing.