Tandem Aza-Wittig/Heterocumulene-Mediated Annulation: Synthesis of Chromeno[2,3-d]pyrimidin-4-ones

The carbodiimides obtained from the reaction of ethyl 7-hydroxy-4-phenyl-2-[(triphenyl-λ5-phosphanylidene)amino]-4H-chromene-3-carboxylate with phenyl isocyanate reacted with different alkyl- and arylamines in the presence of sodium ethoxide to afford a series of chromeno[2,3-d]pyrimidin-4-one derivatives in good yields.

Authors

Magda A. Barsy
Haval A. Hussein (ORCID: https://orcid.org/0000-0002-1626-0523)
Mohamed I. Hassan (ORCID: https://orcid.org/0000-0001-6608-2369)
Mohamed A. Khalil
Eman A. El Rady
Fawi M. Abd El Latif

Institutions

Al Baha University (SA)
Aswan University (EG)

Publication Details

Journal: Russian Journal of Organic Chemistry
Published: 2025-01-01
DOI: https://doi.org/10.1134/s1070428024603066
Primary Topic: Quinazolinone synthesis and applications
Type: article
Field-Weighted Citation Impact: 0.00

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article

Tandem Aza-Wittig/Heterocumulene-Mediated Annulation: Synthesis of Chromeno[2,3-d]pyrimidin-4-ones

Magda A. Barsy, Haval A. Hussein, Mohamed I. Hassan, Mohamed A. Khalil et al.

Jan 1, 2025

Russian Journal of Organic Chemistry

Quinazolinone synthesis and applications

article

Tandem Aza-Wittig/Heterocumulene-Mediated Annulation: Synthesis of Chromeno[2,3-d]pyrimidin-4-ones

Magda A. Barsy, Haval A. Hussein, Mohamed I. Hassan, Mohamed A. Khalil, Eman A. El Rady, Fawi M. Abd El Latif

January 1, 2025article en

Abstract

The carbodiimides obtained from the reaction of ethyl 7-hydroxy-4-phenyl-2-[(triphenyl-λ5-phosphanylidene)amino]-4H-chromene-3-carboxylate with phenyl isocyanate reacted with different alkyl- and arylamines in the presence of sodium ethoxide to afford a series of chromeno[2,3-d]pyrimidin-4-one derivatives in good yields.

Russian Journal of Organic ChemistryVol. 61(1)

Al Baha University (SA), Aswan University (EG)

Openalex Percentile: Top 95%

Quinazolinone synthesis and applications

DOI Source OpenAlex

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