Relationship between serum ferritin and proinflammatory markers in late pregnancy: An exploratory analysis from Cartagena, Colombia

We observed direct and mild associations of serum iron markers (serum ferritin, hemoglobin, and hematocrit) with lymphocyte counts. The inflammation marker, IL-6, was mildly associated with serum ferritin levels in late pregnancy. Women with elevated white blood cell counts and serum ferritin levels tended to have infants with lower birth weights. This fact suggests a potential involvement of iron in inflammatory processes during pregnancy, and conditions associated with inflammation in the final trimester may have adverse effects on perinatal outcomes.

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Publication Details

Journal
Biomédica
Published
2025-03-28
DOI
https://doi.org/10.7705/biomedica.7467
Citations
2
Primary Topic
Iron Metabolism and Disorders
Type
article
Field-Weighted Citation Impact
3.54
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article

Relationship between serum ferritin and proinflammatory markers in late pregnancy: An exploratory analysis from Cartagena, Colombia

Josefina Zakzuk, Alejandra Puerto, Nelson Rafael Alvis Zakzuk, Nelson Alvis‐Guzmán et al.
2 citations
Biomédica
Iron Metabolism and Disorders
3.54
article

Relationship between serum ferritin and proinflammatory markers in late pregnancy: An exploratory analysis from Cartagena, Colombia

Josefina Zakzuk, Alejandra Puerto, Nelson Rafael Alvis Zakzuk, Nelson Alvis‐Guzmán, Walter Annicchiarico
article en
2 citations

Abstract

We observed direct and mild associations of serum iron markers (serum ferritin, hemoglobin, and hematocrit) with lymphocyte counts. The inflammation marker, IL-6, was mildly associated with serum ferritin levels in late pregnancy. Women with elevated white blood cell counts and serum ferritin levels tended to have infants with lower birth weights. This fact suggests a potential involvement of iron in inflammatory processes during pregnancy, and conditions associated with inflammation in the final trimester may have adverse effects on perinatal outcomes.

BiomédicaVol. 45(1)
University of Cartagena (CO), Universidad Pontificia Bolivariana (CO), University of the Coast (CO)
Good health and well-being
Openalex Percentile: Top 9%
Iron Metabolism and Disorders
3.54
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Relationship between serum ferritin and proinflammatory markers in late pregnancy: An exploratory analysis from Cartagena, Colombia — Josefina Zakzuk, Alejandra Puerto, et al. · Biomédica (2025) | TGRS Research Map | TGRS