Pathological response guides adjuvant 5-fluorouracil, leucovorin, oxaliplatin, and docetaxel (FLOT) chemotherapy in surgically resected gastro-oesophageal cancer (SPACE-FLOT): international cohort study

Pathological response to neoadjuvant FLOT may guide the use of adjuvant FLOT, enabling personalized approaches to treatment.

Authors

Publication Details

Journal
British journal of surgery
Published
2025-03-28
DOI
https://doi.org/10.1093/bjs/znaf056
Citations
7
Primary Topic
Gastric Cancer Management and Outcomes
Type
article
Field-Weighted Citation Impact
10.63

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article

Pathological response guides adjuvant 5-fluorouracil, leucovorin, oxaliplatin, and docetaxel (FLOT) chemotherapy in surgically resected gastro-oesophageal cancer (SPACE-FLOT): international cohort study

Geraldine Ooi, Jacky Lu, David I. Watson, Vijayaragavan Muralidharan et al.
7 citations
British journal of surgery
Gastric Cancer Management and Outcomes
10.63
article

Pathological response guides adjuvant 5-fluorouracil, leucovorin, oxaliplatin, and docetaxel (FLOT) chemotherapy in surgically resected gastro-oesophageal cancer (SPACE-FLOT): international cohort study

Geraldine Ooi, Jacky Lu, David I. Watson, Vijayaragavan Muralidharan, Mei Sien Liew, Amy C. Edmondson, Rod Jacobs, Suraj Surendran, Ryan Newbold, Deanna Lee, Joshua N. Hammerschlag, Joseph Jaya, James M. Wilkins, Harsh Kanhere, Amy Crowe, Alain Nguyen, Marek Bąk, Paolo De Martini, Thomas Murphy, Niall Dempster, Matthew Read, Krinal Mori, Mark I. van Berge Henegouwen, Guillaume Piessen, Felicia C. Huynh, Nicholas Evennett, B. Mark Smithers, Sam Alhayo, David S. Liu, Sivakumar Gananadha, Brendan Desmond, Aya Siblini, Kunal Bhanot, Lynn Chong, Michael Bozin, Adam John Frankel, Ahmad Aly, Kevin Lah, Margaret M Lee, Bas P. L. Wijnhoven, Mo Ballal, David Williams, Chao Cheng, Swathikan Chidambaram, Joe Wei, Monica Gualtierotti, Rukshan Ranjan, Sarah A. Martin, Ben Gibbons, Suzanne Sarah Gisbertz, Siang Wei Gan, Enoch Wong, Kyungchul Kim, Inian Samarasam, Ashray Rajagopalan, Lorenzo Ferri, David Lok Hang Chan, Sotiris Mastoridis, Aadil Rahim, James Walmsley, Stephen Barnett, Su Kah Goh, Michalis Koullouros, Jonathan Yeung, Jurstine Daruwalla, Garett Smith, Richard van Hillegersberg, Helen Jaretzke, Yat Cheung Chung, Emily Moran, Ramesh Gurunathan, Sean R. Stevens, Kammy Keywani, Robert Bohmer, Darren Wong, Neil D. Merrett, Janine Thomas, Louise Jackett, Jelle P. Ruurda, Jonathan Tiong, Ewen A. Griffiths, Wael Jamel, Katie L. Whytock, Fredrik Klevebro, Shantanu Joglekar, Jenny Choi, Jason Robertson, Joel D’Souza, Iain G. Thomson, M H Pang, A. Gower, Tim Bright, Sam Owen-Smith, Brian C. Trainor, Yosuke Okamura, Claire L. Donohoe, Pietro Maria Lombardi, Sharon Pattison, Rosemary Ho, Areeb Mian, Eugene Kwong Fei Leong, M. Soo, Andrew P. Barbour, Saania Peeroo, Alexander W. Phillips, D. C. Gotley, Eve Hopping, Jeremy Granger, Negine Paul, Magnus Nilsson, Yi-Tzu Linda Lin, S. Phillips, Aaditya Narendra, Pooja Prasad, Niall C. Tebbutt, Charlène van der Zijden, Jimmy Bok Yan So, Yick Ho Lam, Lauren R. Kennedy-Metz, Daryl Kai Ann Chia, Justine Lerooy, Vipin Khandelwal, Lianne Triemstra, Mohammed Al Azzawi, Chun Chan, Tvisha Ijner, Zhen Zhou, Eunice Lee, Steven Tran, Yahya Al-Habbal, Mary Ann Johnson, Giovanni Ferrari, Sheraz Markar, Douglas Wood, Christina McVeay, Cuong Duong, Chon Hann Liew, Frances Allison, Andrew D MacCormick, Val Usatoff, Alexandra Gordon, Shaun Chew, Michael Michael, Riteshkumar Patel, BS Ko, David Chan, Simon Bann, Aldenb Lorenzo, Girish Pande, Katheryn Hall, F H, John Reynolds, James Tan, Evin Doyle, Nicholas Eikelboom, Rachel McLay-Barnes, Frida Bushati
article en
7 citations

Abstract

Pathological response to neoadjuvant FLOT may guide the use of adjuvant FLOT, enabling personalized approaches to treatment.

British journal of surgeryVol. 112(4)
Royal Australasian College of Surgeons, Peter MacCallum Cancer Centre
Partnerships for the goals
Openalex Percentile: Top 2%
Gastric Cancer Management and Outcomes
10.63
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