Evidence Showing Three Layers of Reconstructed Tympanic Membrane After Second Regenerative Treatment
By applying a recently developed RT-TMP, this report describes the first human study confirming the regeneration of the TM consisting of three layers (epidermis, lamina propria, and mucosa) on pathological analyses of the regenerated part at the second RT-TMP. This is a major step toward the goal of TM regeneration that recapitulates the structural properties of the native TM.
Authors
- Yuri Noda (ORCID: https://orcid.org/0000-0001-8041-0074)
- Akihiro Shimamura
- Tomofumi Sakagami
- Hiroshi Iwai (ORCID: https://orcid.org/0000-0003-2646-8173)
- Hiroshi Hidaka (ORCID: https://orcid.org/0000-0001-5214-3159)
Institutions
- Kansai Medical University (JP)
Publication Details
- Journal
- Otology & Neurotology
- Published
- 2025-03-20
- DOI
- https://doi.org/10.1097/mao.0000000000004421
- Primary Topic
- Ear Surgery and Otitis Media
- Type
- article
- Field-Weighted Citation Impact
- 0.00