Impact of Apolipoprotein A-I Infusions on Cardiovascular Events Post-MI by Neutrophil-Lymphocyte Ratio and LDL-Cholesterol Levels
Baseline elevated NLR predicts MACE in post-AMI patients, and CSL112 showed an associated reduction in MACE in patients with elevated NLR and LDL-C ≥100 mg/dL.
Authors
- José Carlos Nicolau (ORCID: https://orcid.org/0000-0002-9680-3689)
- Philippe Gabríel Steg (ORCID: https://orcid.org/0000-0001-6896-2941)
- Charles Michael Gibson (ORCID: https://orcid.org/0000-0002-4857-9125)
- Jurriën M. ten Berg (ORCID: https://orcid.org/0000-0001-5192-886X)
- Basil S. Lewis (ORCID: https://orcid.org/0000-0001-5604-6399)
- Dragoş Vinereanu (ORCID: https://orcid.org/0000-0002-9054-8779)
- Niekbachsh Mohammadnia (ORCID: https://orcid.org/0000-0002-5968-3817)
- Kevin R. Bainey (ORCID: https://orcid.org/0000-0002-5458-4617)
- Kenneth W. Mahaffey (ORCID: https://orcid.org/0000-0002-3791-2148)
- Bronwyn A. Kingwell (ORCID: https://orcid.org/0000-0002-2162-0458)
- Sem A.O.F. Rikken (ORCID: https://orcid.org/0000-0002-4118-9044)
- Gaya Anschuetz
- Stephen James Nicholls (ORCID: https://orcid.org/0000-0002-9668-4368)
- Robert A. Harrington (ORCID: https://orcid.org/0000-0001-5450-8676)
- Gerald Chi (ORCID: https://orcid.org/0000-0002-8371-1689)
- Renato D. Lópes (ORCID: https://orcid.org/0000-0003-2999-4961)
- Serge Korjian (ORCID: https://orcid.org/0000-0003-0605-8337)
- Ton Oude Ophuis
- Arnoud W.J. van ‘t Hof (ORCID: https://orcid.org/0000-0002-2344-7564)
- Paul M. Ridker (ORCID: https://orcid.org/0000-0003-1249-4522)
- Danielle Duffy (ORCID: https://orcid.org/0000-0002-5037-8189)
- Saloua El Messaoudi (ORCID: https://orcid.org/0009-0006-0804-2071)
- M. Cecilia Bahit (ORCID: https://orcid.org/0000-0001-6179-4076)
- Christoph Bode
- Peter Libby
- Jan H. Cornel
- Shaun G. Goodman
- R. Mehran
- H. D. White
Institutions
- Brigham and Women's Hospital (US)
- Beth Israel Deaconess Medical Center (US)
- University Health Network (CA)
- Harvard University (US)
- Radboud University Nijmegen (NL)
- Inserm (FR)
- University of Freiburg (DE)
- Carol Davila University of Medicine and Pharmacy (RO)
- Université Paris Cité (FR)
- Cornell University (US)
- Cardiovascular Institute of the South (US)
- Maastricht University Medical Centre (NL)
- Auckland City Hospital (NZ)
- University of Alberta Hospital (CA)
- Radboud University Medical Center (NL)
- Maastricht University (NL)
- Clinical Research Institute (US)
- Noordwest Ziekenhuisgroep (NL)
- Assistance Publique – Hôpitaux de Paris (FR)
- Mount Sinai Hospital (US)
- St. Antonius Ziekenhuis (NL)
- Baim Institute for Clinical Research (US)
- CSL (United States) (US)
- Carmel Medical Center (IL)
- Canisius-Wilhelmina Ziekenhuis (NL)
- Instituto de Neurología Cognitiva (AR)
- Hôpital Bichat-Claude-Bernard (FR)
- Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (BR)
- Center for Clinical Research (United States) (US)
- CSL (Australia) (AU)
- Weill Cornell Medicine (US)
- Stanford University (US)
Publication Details
- Journal
- JACC Advances
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1016/j.jacadv.2025.101727
- Citations
- 1
- Primary Topic
- Adipokines, Inflammation, and Metabolic Diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.35
Funders
- Bristol-Myers Squibb
- Pfizer
- AstraZeneca
- Bayer Corporation
- CSL Behring
- Janssen Pharmaceuticals
- Daiichi Sankyo Europe