Pathogens Causing Surgical Site Infections After Lower Uterine Caesarean Sections and Recommendations for Antibiotic Guidelines

Current Australian guidelines may not be appropriate in a considerable proportion of patients with LUCS SSIs, and patients with systemic features of infection should receive antibiotics with activity against P. aeruginosa and MRSA. Critically ill patients with features of sepsis or septic shock should be administered a carbapenem agent which has activity against AmpC/ESBL producing Enterobacterales, instead of piperacillin/tazobactam. Staphylococcus lugdunensis may be an under recognised pathogen in LUCS SSIs. This study also highlighted the importance of wound site sampling in SSIs to establish appropriate directed antimicrobial therapy.

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Publication Details

Journal
Australian and New Zealand Journal of Obstetrics and Gynaecology
Published
2025-03-30
DOI
https://doi.org/10.1111/ajo.70034
Primary Topic
Surgical site infection prevention
Type
article
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article

Pathogens Causing Surgical Site Infections After Lower Uterine Caesarean Sections and Recommendations for Antibiotic Guidelines

Penelope Clohessy, Andrew Walczak, Henco Nel, B. Yeo et al.
Australian and New Zealand Journal of Obstetrics and Gynaecology
Surgical site infection prevention
article

Pathogens Causing Surgical Site Infections After Lower Uterine Caesarean Sections and Recommendations for Antibiotic Guidelines

Penelope Clohessy, Andrew Walczak, Henco Nel, B. Yeo, Rebecca McCann
article en

Abstract

Current Australian guidelines may not be appropriate in a considerable proportion of patients with LUCS SSIs, and patients with systemic features of infection should receive antibiotics with activity against P. aeruginosa and MRSA. Critically ill patients with features of sepsis or septic shock should be administered a carbapenem agent which has activity against AmpC/ESBL producing Enterobacterales, instead of piperacillin/tazobactam. Staphylococcus lugdunensis may be an under recognised pathogen in LUCS SSIs. This study also highlighted the importance of wound site sampling in SSIs to establish appropriate directed antimicrobial therapy.

Australian and New Zealand Journal of Obstetrics and GynaecologyVol. 65(6)
The University of Western Australia (AU), Government of Western Australia Department of Health (AU), Sir Charles Gairdner Hospital (AU), Queen Elizabeth II Medical Centre (AU), Pathwest Laboratory Medicine (AU)
Good health and well-being
Openalex Percentile: Top 89%
Surgical site infection prevention
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Pathogens Causing Surgical Site Infections After Lower Uterine Caesarean Sections and Recommendations for Antibiotic Guidelines — Penelope Clohessy, Andrew Walczak, et al. · Australian and New Zealand Journal of Obstetrics and Gynaecology (2025) | TGRS Research Map | TGRS