A correction for modeling radial, spiral, and <scp>PROPELLER</scp> dynamic contrast‐enhanced data: Time‐averaged extended Tofts
Our study demonstrates that time-averaged signals lead to decreased accuracy and precision in pharmacokinetic modeling when ignored. We suggest using our corrected pharmacokinetic model when performing dynamic contrast-enhanced with variable-density acquisitions, especially for dynamic scan times that are 8 s and longer.
Authors
- Oliver J. Gurney‐Champion (ORCID: https://orcid.org/0000-0003-1750-6617)
- Eric Schrauben (ORCID: https://orcid.org/0000-0002-7922-3615)
- Marian Troelstra (ORCID: https://orcid.org/0000-0001-6748-4810)
- Nienke Wassenaar (ORCID: https://orcid.org/0000-0002-3668-944X)
- Natalia Korobova
Institutions
- Amsterdam University Medical Centers (NL)
- Cancer Center Amsterdam (NL)
Publication Details
- Journal
- Magnetic Resonance in Medicine
- Published
- 2025-03-30
- DOI
- https://doi.org/10.1002/mrm.30514
- Primary Topic
- MRI in cancer diagnosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- KWF Kankerbestrijding
- Cancer Center Amsterdam