Assessing Transendothelial Electrical Resistance in an In Vitro Blood-Brain Barrier Model

Source: Kuzmanov, I., et al. An In Vitro Model of the Blood-brain Barrier Using Impedance Spectroscopy: A Focus on T Cell-endothelial Cell Interaction. J. Vis. Exp. (2016) This video demonstrates a method for assessing transendothelial electrical resistance (TEER) in mouse brain microvascular endothelial cells in vitro. A high TEER value indicates intact endothelial cell junctions, while the addition of activated T cells lowers the TEER value, reflecting disruption of the junctional barrier.

Publication Details

Journal: Journal of Visualized Experiments
Published: 2025-03-31
DOI: https://doi.org/10.3791/23193
Primary Topic: EEG and Brain-Computer Interfaces
Type: article
Field-Weighted Citation Impact: 0.00

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article

Assessing Transendothelial Electrical Resistance in an In Vitro Blood-Brain Barrier Model

Mar 31, 2025

Journal of Visualized Experiments

EEG and Brain-Computer Interfaces

article

Assessing Transendothelial Electrical Resistance in an In Vitro Blood-Brain Barrier Model

March 31, 2025article en

Abstract

Journal of Visualized Experiments

Openalex Percentile: Top 94%

EEG and Brain-Computer Interfaces

DOI Source OpenAlex

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Assessing Transendothelial Electrical Resistance in an In Vitro Blood-Brain Barrier Model · Journal of Visualized Experiments (2025) | TGRS Research Map | TGRS