Two undescribed iridoids from the flowers of <i>Sesamum indicum</i> L.

From the flowers of <i>Sesamum indicum</i> L., two novel iridoid compounds sesamiridol (<b>1</b>) and sesamiridoside (<b>2</b>) have been successfully isolated. Alongside these, five known iridoids were identified: lamiolactone (<b>3</b>), sesamoside (<b>4</b>), lamalbide (<b>5</b>), shanzhiside methyl ester (<b>6</b>), phloyoside III (<b>7</b>). The two-dimensional structures of compounds <b>1</b> and <b>2</b> were ascertained by means of IR, UV, NMR, and HR-ESI-MS, corroborated by comparison with relevant literature data. The configurations of these novel compounds were clarified <i>via</i> NOESY spectroscopy, ECD calculations, and acid hydrolysis. Moreover, an evaluation of the antioxidant activities of all compounds were conducted.