Insights from Vitamin D levels among psoriasis patients in India

Psoriasis is a chronic inflammatory skin condition caused by immune system dysfunction characterized by excessive growth of epidermal keratinocytes and inflammatory cells in the dermis and epidermis. The epidermis plays a role in vitamin D synthesis through sunlight exposure. A link between low vitamin D levels and psoriasis is known. Therefore, it is of interest to assess Vitamin D among psoriasis patients to gain insights. Data shows that patients suffering from moderate to severe psoriasis exhibit lower levels of vitamin D when compared to those in the control group. Vitamin D influences keratinocyte proliferation and maturation and hence its role in the management of the condition is realised. However, the effective use of dietary vitamin D or oral supplements for psoriasis treatment remains an unresolved clinical issue with on-going debate regarding the evidence of its benefits.