Carboxyhemoglobin and Methemoglobin as Biomarkers of Hemolysis and Mortality in Acute Respiratory Distress Syndrome Treated by Veno-Venous Extracorporeal Membrane Oxygenation
In patients with ARDS and ECMO, Met-Hb plasma concentrations were independently associated with hemolytic events. Both, mean CO-Hb and Met-Hb levels were associated with ICU mortality. These markers and their associated cutoff values might serve as a risk indicator in clinical practice.
Authors
- Victoria Bünger (ORCID: https://orcid.org/0000-0003-3557-2423)
- Alexander Krannich (ORCID: https://orcid.org/0000-0002-4025-6495)
- Claudia Spies (ORCID: https://orcid.org/0000-0002-1062-0495)
- Jan A. Graw (ORCID: https://orcid.org/0000-0002-6920-8868)
- Wolfgang M. Kuebler (ORCID: https://orcid.org/0000-0003-4100-2961)
- Steffen Weber‐Carstens (ORCID: https://orcid.org/0000-0001-7405-0172)
- Felix Balzer (ORCID: https://orcid.org/0000-0003-1575-2056)
- Oliver Hunsicker (ORCID: https://orcid.org/0000-0002-3998-409X)
- Mario Menk (ORCID: https://orcid.org/0000-0003-1340-9211)
Institutions
- Humboldt-Universität zu Berlin (DE)
- University Hospital Ulm (DE)
- University Hospital Carl Gustav Carus (DE)
- Freie Universität Berlin (DE)
- Technische Universität Dresden (DE)
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- Anesthesia & Analgesia
- Published
- 2025-03-31
- DOI
- https://doi.org/10.1213/ane.0000000000007495
- Primary Topic
- Hemoglobin structure and function
- Type
- article
- Field-Weighted Citation Impact
- 0.00