Atractylenolide-Ⅲ binds non-structural protein-1 to suppress influenza A by modulating macrophage polarization and alternative polyadenylation
ACT-Ⅲ inhibits IAV replication and viral pneumonia by binding to NS1, showing potential as a therapeutic agent for IAV treatment.
Authors
- Jie Yang (ORCID: https://orcid.org/0000-0002-8348-7250)
- Jiayin Qiu
- Guanxiang Liang (ORCID: https://orcid.org/0000-0002-7367-2516)
- Qinghua Mei
- Wenjiao Wu
- Shuwen Liu (ORCID: https://orcid.org/0000-0001-6346-5006)
- Dan Li (ORCID: https://orcid.org/0000-0002-1264-5952)
- Yan Yang (ORCID: https://orcid.org/0000-0003-0887-2770)
- H. Liang (ORCID: https://orcid.org/0000-0002-8036-4423)
- Zhixuan Chen (ORCID: https://orcid.org/0000-0003-1626-0547)
- Huiyi Guo
- Jinlong Liang
Institutions
- Zhejiang Chinese Medical University (CN)
- Jinan University (CN)
- Guangdong Pharmaceutical University (CN)
- Second Affiliated Hospital of Guangzhou Medical University (CN)
- Southern Medical University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Phytomedicine
- Published
- 2025-03-31
- DOI
- https://doi.org/10.1016/j.phymed.2025.156704
- Citations
- 3
- Primary Topic
- Immune Response and Inflammation
- Type
- article
- Field-Weighted Citation Impact
- 2.39