Schistosoma mansoni x S. haematobium hybrids frequently infecting sub-Saharan migrants in southeastern Europe: Egg DNA genotyping assessed by RD-PCR, sequencing and cloning
This study contributes to: (i) a better understanding of the heterospecific hybrids between S. mansoni and S. haematobium from the genetic point of view; (ii) it shows the frequency with which they are entering non-endemic countries, such as Spain and consequently in Europe; (iii) it determines the diversity of hybrid eggs and haplotypes that can occur within a single patient, e.g., up to two types of hybrids involving three Schistosoma species and up to six different haplotypes; (iv) it provides information to be considered in clinical presentations, diagnosis, responses to treatment and epidemiological impact in relation to possible transmission and establishment in non-endemic areas.
Authors
- Jérôme Boissier (ORCID: https://orcid.org/0000-0002-0793-3108)
- Marta Reguera-Gómez
- Alejandra De Elías-Escribano (ORCID: https://orcid.org/0000-0002-6147-0300)
- Patricio Artigas (ORCID: https://orcid.org/0000-0002-2815-1324)
- M. Dolores Bargues (ORCID: https://orcid.org/0000-0003-2347-7269)
- María Pilar Luzón-García (ORCID: https://orcid.org/0000-0001-5260-7072)
- José Vázquez-Villegas (ORCID: https://orcid.org/0000-0002-3925-7263)
- Joaquín Salas-Coronas (ORCID: https://orcid.org/0000-0002-4302-7022)
- Santiago Mas‐Coma (ORCID: https://orcid.org/0000-0002-1685-7004)
- María Isabel Cabeza-Barrera
Institutions
- Centre National de la Recherche Scientifique (FR)
- Université de Perpignan (FR)
- Ifremer (FR)
- Universitat de València (ES)
- Université de Montpellier (FR)
- Instituto de Salud Carlos III (ES)
- Hospital de Poniente (ES)
- Centro de Investigación Biomédica en Red (ES)
- University of Almería (ES)
Publication Details
- Journal
- PLoS neglected tropical diseases
- Published
- 2025-03-31
- DOI
- https://doi.org/10.1371/journal.pntd.0012942
- Citations
- 9
- Primary Topic
- Parasites and Host Interactions
- Type
- article
- Field-Weighted Citation Impact
- 18.43
Funders
- American Concrete Institute Foundation
- European Commission
- Generalitat Valenciana
- Universitat de València
- Ministerio de Ciencia e Innovación
- Junta de Andalucía
- Instituto de Salud Carlos III
- European Regional Development Fund
- European Social Fund