International multispecialty expert physician preoperative identification of extranodal extension in patients with oropharyngeal cancer using computed tomography: Prospective blinded human inter‐observer performance evaluation
Diagnostic performance for iENE on CT in HPV-positive OPC remains poor across specialties, with high variability and low accuracy. These findings highlight the need for automated systems or improved imaging methods to enhance iENE assessments.
Authors
- Jeffrey P. Guenette (ORCID: https://orcid.org/0000-0002-4684-5469)
- Jack Phan (ORCID: https://orcid.org/0000-0001-5977-6004)
- Renjie He (ORCID: https://orcid.org/0000-0001-9166-6286)
- Serageldin Kamel (ORCID: https://orcid.org/0000-0002-0046-4337)
- Antti A. Mäkitie (ORCID: https://orcid.org/0000-0002-0451-2404)
- Frank Hoebers (ORCID: https://orcid.org/0000-0002-4317-9181)
- Onur Sahin (ORCID: https://orcid.org/0000-0003-2191-5659)
- G. Brandon Gunn (ORCID: https://orcid.org/0000-0001-8197-0380)
- Benjamin H. Kann (ORCID: https://orcid.org/0000-0002-4313-2754)
- Kareem A. Wahid (ORCID: https://orcid.org/0000-0002-0503-0175)
- Vlad C. Sandulache (ORCID: https://orcid.org/0000-0002-9205-385X)
- Shalin J. Shah (ORCID: https://orcid.org/0000-0002-1622-8443)
- Christina Setareh Sharafi (ORCID: https://orcid.org/0000-0002-7560-2204)
- Jaakko Sahlsten (ORCID: https://orcid.org/0000-0002-7364-6502)
- Joel Jaskari
- Katherine A. Hutcheson (ORCID: https://orcid.org/0000-0003-3710-5706)
- Andrew G. Sikora (ORCID: https://orcid.org/0000-0002-8357-8435)
- Cem Dede (ORCID: https://orcid.org/0000-0002-0543-9325)
- Jussi Hirvonen (ORCID: https://orcid.org/0000-0002-0368-3746)
- Nicolette Taku (ORCID: https://orcid.org/0000-0003-2710-9404)
- Melissa Chen (ORCID: https://orcid.org/0000-0002-3274-2653)
- Mohamed A. Naser (ORCID: https://orcid.org/0000-0003-1020-4966)
- Shekhar Khanpara (ORCID: https://orcid.org/0000-0002-9127-196X)
- Clifton D. Fuller (ORCID: https://orcid.org/0000-0002-5264-3994)
- Eduardo M. Diaz (ORCID: https://orcid.org/0000-0001-7268-5166)
- Anastasios Maniakas (ORCID: https://orcid.org/0000-0002-4354-2841)
- Kristen B. Pytynia (ORCID: https://orcid.org/0000-0002-4471-6997)
- Adam S. Garden (ORCID: https://orcid.org/0000-0001-7926-2641)
- Kim O. Learned (ORCID: https://orcid.org/0000-0002-5125-4022)
- Gregory M. Chronowski (ORCID: https://orcid.org/0000-0001-8878-7140)
- Kimmo Kaski (ORCID: https://orcid.org/0000-0002-3805-9687)
- Carol M. Lewis (ORCID: https://orcid.org/0000-0003-3131-4013)
- Jeffrey N. Myers (ORCID: https://orcid.org/0000-0003-4767-3408)
- Ryan P. Goepfert (ORCID: https://orcid.org/0000-0002-3291-841X)
- Nandita Guha‐Thakurta (ORCID: https://orcid.org/0000-0002-3735-5361)
- Jason M. Johnson (ORCID: https://orcid.org/0000-0001-7724-5784)
- Stephen Y. Lai (ORCID: https://orcid.org/0000-0001-8301-7286)
- Amy C. Moreno (ORCID: https://orcid.org/0000-0001-6762-6807)
- Miriam N. Lango (ORCID: https://orcid.org/0000-0003-0736-7473)
- Dawid Schellingerhout (ORCID: https://orcid.org/0000-0003-3659-435X)
- Abdallah Mohamed (ORCID: https://orcid.org/0000-0003-2064-7613)
- Anna Lee (ORCID: https://orcid.org/0000-0002-9114-1815)
- D.I. Rosenthal
- Kristofer Nyman (ORCID: https://orcid.org/0000-0003-4150-3141)
- Diana Kaya (ORCID: https://orcid.org/0000-0002-6494-855X)
- Moran Amit
Institutions
- Brigham and Women's Hospital (US)
- University of Helsinki (FI)
- The University of Texas MD Anderson Cancer Center (US)
- Harvard University (US)
- Baylor College of Medicine (US)
- Helsinki University Hospital (FI)
- Dana-Farber Cancer Institute (US)
- Tampere University Hospital (FI)
- Tampere University (FI)
- Dana-Farber Brigham Cancer Center (US)
- Aalto University (FI)
Publication Details
- Journal
- Cancer
- Published
- 2025-03-30
- DOI
- https://doi.org/10.1002/cncr.35815
- Citations
- 4
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 7.39
Funders
- National Cancer Institute