Role of Streptococcus mutants Biofilm in Dental Caries

Abstract Dental caries is a common chronic disease affecting tooth of many subjects at different ages due to biofilm-mediated oral bacterial infection. Streptococcus mutans is regarded as a pivotal cariogenic bacterium responsible for dental caries and plaque formation. It produces exopolysaccharides on the surface of the tooth promoting the colonization of cariogenic bacteria and dental biofilm development. Formation of this biofilm can be prevented by using different antimicrobial agents such as BlueM mouthwash, polypyrrole, natural flavonoids, and endocannabinoid anandamide.