Generalized purulent necrotic lesions in diabetic foot syndrome

Objective. To analyze the scheme of complex treatment of patients with diabetic foot syndrome (DFS) developed by the authors, which includes three-stage surgical treatment, as well as infusion and conservative therapy. Material and methods. The study involved 606 patients with DFS, of which 54.1% had purulent-necrotic lesions of lower limbs tissues against the background of diabetes mellitus, and 2% had complicated syndrome of systemic inflammatory reaction (sepsis). Results. The treatment results were evaluated in the form of three outcomes: favorable (preservation of the lower limb support function + cessation of clinical manifestations of generalized infection) – in 44.4% of cases, unfavorable (lower limb amputation without preservation of the support function + cessation of clinical manifestations of generalized infection) – in 22.3%, lethal – in 33.3%. Conclusion. The proposed stage and sequence of treatment of patients with generalized forms of pathology on the background of DFS allow to reduce the frequency of high amputations of lower limbs and improve the quality of life of patients of this category.

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Publication Details

Journal
Vrach
Published
2025-03-19
DOI
https://doi.org/10.29296/25877305-2025-03-08
Primary Topic
Diabetic Foot Ulcer Assessment and Management
Type
article
Field-Weighted Citation Impact
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article

Generalized purulent necrotic lesions in diabetic foot syndrome

P. S. Lukin, Константин Александрович Корейба, A. R. Minabutdinov, E. Krivoshchekov
Vrach
Diabetic Foot Ulcer Assessment and Management
article

Generalized purulent necrotic lesions in diabetic foot syndrome

P. S. Lukin, Константин Александрович Корейба, A. R. Minabutdinov, E. Krivoshchekov
article en

Abstract

Objective. To analyze the scheme of complex treatment of patients with diabetic foot syndrome (DFS) developed by the authors, which includes three-stage surgical treatment, as well as infusion and conservative therapy. Material and methods. The study involved 606 patients with DFS, of which 54.1% had purulent-necrotic lesions of lower limbs tissues against the background of diabetes mellitus, and 2% had complicated syndrome of systemic inflammatory reaction (sepsis). Results. The treatment results were evaluated in the form of three outcomes: favorable (preservation of the lower limb support function + cessation of clinical manifestations of generalized infection) – in 44.4% of cases, unfavorable (lower limb amputation without preservation of the support function + cessation of clinical manifestations of generalized infection) – in 22.3%, lethal – in 33.3%. Conclusion. The proposed stage and sequence of treatment of patients with generalized forms of pathology on the background of DFS allow to reduce the frequency of high amputations of lower limbs and improve the quality of life of patients of this category.

Vrach
Kazan State Medical University (RU), Perm State Medical Academy (RU), Ministry of Health of the Russian Federation (RU), Samara State Medical University (RU)
Openalex Percentile: Top 91%
Diabetic Foot Ulcer Assessment and Management
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Generalized purulent necrotic lesions in diabetic foot syndrome — P. S. Lukin, Константин Александрович Корейба, et al. · Vrach (2025) | TGRS Research Map | TGRS