Raising the Age for Starting Colonoscopy to 35 Years for Individuals With path_MSH6 Carriers May Lead to Missed Opportunities for Detecting Advanced Neoplasia in a Notable Percentage of Carriers
Our findings suggest that the recommendation to raise the age for initiating colonoscopy to 35 years for path_MSH6 carriers merits careful consideration because there is a possibility that AN may not be detected. Given the limited size of our study and the potential for ascertainment bias, we encourage further research to explore and validate our findings.
Authors
- Lior H. Katz (ORCID: https://orcid.org/0000-0003-2885-7279)
- Revital Kariv (ORCID: https://orcid.org/0000-0002-3831-9020)
- Hana Strul
- Aasem Abu Shtaya (ORCID: https://orcid.org/0000-0002-6873-3193)
- Elizabeth Half (ORCID: https://orcid.org/0000-0002-4508-8670)
- Itay Maza (ORCID: https://orcid.org/0000-0003-3877-6501)
- Zohar Levi (ORCID: https://orcid.org/0000-0003-2456-8891)
- Tom Konikoff (ORCID: https://orcid.org/0000-0003-4915-111X)
- Guy Rosner (ORCID: https://orcid.org/0000-0003-1044-4935)
- Yael Goldberg (ORCID: https://orcid.org/0000-0002-9855-9472)
- Nathan Gluck (ORCID: https://orcid.org/0000-0001-5503-488X)
- Rachel Gingold‐Belfer (ORCID: https://orcid.org/0000-0002-2831-4402)
- Rakefet Chen‐Shtoyerman (ORCID: https://orcid.org/0000-0002-5055-5907)
- Naim Abu‐Freha (ORCID: https://orcid.org/0000-0002-4844-3308)
- Ido Laish (ORCID: https://orcid.org/0000-0003-0324-9998)
- Hadar Edelman-Klapper (ORCID: https://orcid.org/0000-0003-2698-0492)
- Gili Reznick Levi (ORCID: https://orcid.org/0000-0002-7490-8965)
- Alex Vilkin
- Maya Aharoni Golan
Institutions
- Ben-Gurion University of the Negev (IL)
- Rafael Advanced Defense Systems (Israel) (IL)
- Tel Aviv University (IL)
- Technion – Israel Institute of Technology (IL)
- Hebrew University of Jerusalem (IL)
- Tel Aviv Sourasky Medical Center (IL)
- Sheba Medical Center (IL)
- Hadassah Medical Center (IL)
- Kaplan Medical Center (IL)
- Rabin Medical Center (IL)
- Soroka Medical Center (IL)
- Rambam Health Care Campus (IL)
- The Technological College of Beer Sheva (IL)
- Carmel Medical Center (IL)
- Ariel University (IL)
Publication Details
- Journal
- The American Journal of Gastroenterology
- Published
- 2025-03-31
- DOI
- https://doi.org/10.14309/ajg.0000000000003431
- Citations
- 2
- Primary Topic
- Genetic factors in colorectal cancer
- Type
- article
- Field-Weighted Citation Impact
- 2.94