Optimization of Medical Injection Pump Nozzle Structure Based on CFD

Abstract The internal structure of medical injection pump nozzles often suffers from issues such as excessive internal flow viscosity, leading to the accumulation of drug particles in corners. This results in inefficient delivery of drug microparticles during traditional subcutaneous injections, posing severe challenges to the clinical translation of biopharmaceuticals and microparticle-based drug formulations. By combining fluid mechanics methods, this study innovatively designed a new multi-stage nozzle structure and optimized the parameters of the multi-stage injector. The deficiencies of conventional nozzles were analyzed, and an improved nozzle structure scheme was proposed. Computational fluid dynamics (CFD) simulation technology was employed to verify and optimize the performance of the new structure. Simulation results demonstrated that the improved nozzle structure enhanced drug delivery speed by 18% and increased injection efficiency by 50%.

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Publication Details

Journal
Applied Mathematics and Nonlinear Sciences
Published
2025-01-01
DOI
https://doi.org/10.2478/amns-2025-0838
Primary Topic
Intravenous Infusion Technology and Safety
Type
article
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article

Optimization of Medical Injection Pump Nozzle Structure Based on CFD

Chao Xie
Applied Mathematics and Nonlinear Sciences
Intravenous Infusion Technology and Safety
article

Optimization of Medical Injection Pump Nozzle Structure Based on CFD

Chao Xie
article en

Abstract

Abstract The internal structure of medical injection pump nozzles often suffers from issues such as excessive internal flow viscosity, leading to the accumulation of drug particles in corners. This results in inefficient delivery of drug microparticles during traditional subcutaneous injections, posing severe challenges to the clinical translation of biopharmaceuticals and microparticle-based drug formulations. By combining fluid mechanics methods, this study innovatively designed a new multi-stage nozzle structure and optimized the parameters of the multi-stage injector. The deficiencies of conventional nozzles were analyzed, and an improved nozzle structure scheme was proposed. Computational fluid dynamics (CFD) simulation technology was employed to verify and optimize the performance of the new structure. Simulation results demonstrated that the improved nozzle structure enhanced drug delivery speed by 18% and increased injection efficiency by 50%.

Applied Mathematics and Nonlinear SciencesVol. 10(1)
Hefei University of Technology (CN), Hefei General Machinery Research Institute (China) (CN)
Openalex Percentile: Top 94%
Intravenous Infusion Technology and Safety
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