Atypical presentation of Liposarcoma involving the breast: a case report

A 62-year-old woman presented to our institution with a 3-year history of left-sided breast mass. Diagnostic imaging three years prior suggested the presence of a lipoma with no suspicious findings. The patient noted that the mass continued to grow with no significant clinical symptoms. Imaging revealed a substantial difference in breast size, with the left breast largely occupied by a fatty vascular soft tissue mass. The patient was diagnosed with liposarcoma arising from or infiltrating the pectoralis major and minor muscles. The patient underwent a mastectomy, and the final pathology results confirmed an atypical lipomatous tumour with well-differentiated liposarcoma components. Liposarcoma should be considered and ruled out in cases of any large or growing fatty masses in the breast.

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Publication Details

Journal
Oxford Medical Case Reports
Published
2025-03-28
DOI
https://doi.org/10.1093/omcr/omaf013
Primary Topic
Breast Lesions and Carcinomas
Type
article
Field-Weighted Citation Impact
0.00
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article

Atypical presentation of Liposarcoma involving the breast: a case report

Afsaneh Alikhassi, Aswen Sriranganathan
Oxford Medical Case Reports
Breast Lesions and Carcinomas
article

Atypical presentation of Liposarcoma involving the breast: a case report

Afsaneh Alikhassi, Aswen Sriranganathan
article en

Abstract

A 62-year-old woman presented to our institution with a 3-year history of left-sided breast mass. Diagnostic imaging three years prior suggested the presence of a lipoma with no suspicious findings. The patient noted that the mass continued to grow with no significant clinical symptoms. Imaging revealed a substantial difference in breast size, with the left breast largely occupied by a fatty vascular soft tissue mass. The patient was diagnosed with liposarcoma arising from or infiltrating the pectoralis major and minor muscles. The patient underwent a mastectomy, and the final pathology results confirmed an atypical lipomatous tumour with well-differentiated liposarcoma components. Liposarcoma should be considered and ruled out in cases of any large or growing fatty masses in the breast.

Oxford Medical Case ReportsVol. 2025(4)
Sunnybrook Health Science Centre (CA), University of Ottawa (CA), University of Toronto (CA), Health Sciences Centre (CA), Ottawa University (US)
Good health and well-being
Openalex Percentile: Top 91%
Breast Lesions and Carcinomas
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Atypical presentation of Liposarcoma involving the breast: a case report — Afsaneh Alikhassi, Aswen Sriranganathan · Oxford Medical Case Reports (2025) | TGRS Research Map | TGRS